Title:
HPV INFECTIOUS DISEASE VACCINE
Document Type and Number:
WIPO Patent Application WO/2022/244815
Kind Code:
A1
Abstract:
Provided are lipid particles in which is encapsulated a nucleic acid, whereby: a vaccine for preventing and/or treating an infection by human papillomavirus type-6 and/or type-11 can be provided; and an E6 antibody and an E7 antibody to the human papillomavirus can be expressed. The lipid particles contain: a lipid that is a cationic lipid represented by general formula (Ia); or a pharmaceutically acceptable salt thereof. [In the formula, R1, R2, p, L1 and L2 are defined as described in the specification.]
Inventors:
ONODERA YOSHIKUNI (JP)
TANOUE SUMIKA (JP)
NIWA TAKAKO (JP)
KOIZUMI MAKOTO (JP)
TANOUE SUMIKA (JP)
NIWA TAKAKO (JP)
KOIZUMI MAKOTO (JP)
Application Number:
PCT/JP2022/020713
Publication Date:
November 24, 2022
Filing Date:
May 18, 2022
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C12N15/88; A61K9/10; A61K9/14; A61K31/7088; A61K31/7115; A61K39/12; A61K47/18; A61K47/24; A61K47/28; A61K47/34; A61K48/00; A61P11/00; A61P15/00; A61P31/20; A61P37/04; C12N15/34
Domestic Patent References:
| WO2015005253A1 | 2015-01-15 | |||
| WO2021095838A1 | 2021-05-20 | |||
| WO2015005253A1 | 2015-01-15 |
Foreign References:
| JP2019532657A | 2019-11-14 | |||
| JP2020530765A | 2020-10-29 | |||
| JP2020172500A | 2020-10-22 | |||
| JP2020039341A | 2020-03-19 | |||
| JP2018531290A | 2018-10-25 | |||
| JP2016512553A | 2016-04-28 |
Other References:
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J NATL CANCER INST, vol. 87, 1995, pages 796 - 802
VIRUS RES., vol. 231, 2017, pages 119 - 127
J CLIN VIROL, vol. 32, no. 1, 2005, pages S7 - 15
CELL, vol. 63, 1990, pages 1129 - 36
CANCER RES, vol. 56, 1996, pages 4620 - 4
J VIROL, 1989, pages 2650 - 2656
J VIROL, 1992, pages 1329 - 1335
J VIROL, 1994, pages 5698 - 5705
PROC NATL ACAD SCI U. S. A, vol. 106, 2009, pages 20458 - 63
J INFECT DIS., vol. 219, no. 7, 2019, pages 1016 - 1025
NAT REV CANCER, vol. 6, no. 10, 2006, pages 753 - 763
HUM VACCIN IMMUNOTHER., vol. 8, no. 4, 2012, pages 470 - 478
J. BIOL. CHEM., vol. 267, 1992, pages 16396
J. BIOL. CHEM., vol. 266, 1991, pages 12127
SAMBROOK, J. ET AL.: "Molecular Cloning a Laboratory Manual", 1989
RASHTCHIAN, A., CURRENT OPINION IN BIOTECHNOLOGY, vol. 6, no. 1, 1995, pages 30 - 36
GIBSON D.G. ET AL., SCIENCE, vol. 319, no. 5867, 2008, pages 1215 - 1220
KORMANN, M., NATURE BIOTECHNOLOGY, vol. 29, 2011, pages 154 - 157
J NATL CANCER INST, vol. 87, 1995, pages 796 - 802
VIRUS RES., vol. 231, 2017, pages 119 - 127
J CLIN VIROL, vol. 32, no. 1, 2005, pages S7 - 15
CELL, vol. 63, 1990, pages 1129 - 36
CANCER RES, vol. 56, 1996, pages 4620 - 4
J VIROL, 1989, pages 2650 - 2656
J VIROL, 1992, pages 1329 - 1335
J VIROL, 1994, pages 5698 - 5705
PROC NATL ACAD SCI U. S. A, vol. 106, 2009, pages 20458 - 63
J INFECT DIS., vol. 219, no. 7, 2019, pages 1016 - 1025
NAT REV CANCER, vol. 6, no. 10, 2006, pages 753 - 763
HUM VACCIN IMMUNOTHER., vol. 8, no. 4, 2012, pages 470 - 478
J. BIOL. CHEM., vol. 267, 1992, pages 16396
J. BIOL. CHEM., vol. 266, 1991, pages 12127
SAMBROOK, J. ET AL.: "Molecular Cloning a Laboratory Manual", 1989
RASHTCHIAN, A., CURRENT OPINION IN BIOTECHNOLOGY, vol. 6, no. 1, 1995, pages 30 - 36
GIBSON D.G. ET AL., SCIENCE, vol. 319, no. 5867, 2008, pages 1215 - 1220
KORMANN, M., NATURE BIOTECHNOLOGY, vol. 29, 2011, pages 154 - 157
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (JP)
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