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Title:
HSP90 INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2007/138994
Kind Code:
A1
Abstract:
Disclosed is a compound represented by the general formula (1) or a pharmaceutically acceptable salt thereof: (1) Also disclosed is a pharmaceutical composition comprising the compound.

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Inventors:
TSUKUDA TAKUO (JP)
KAWASAKI KEN-ICHI (JP)
KOMIYAMA SUSUMU (JP)
ISSHIKI YOSHIAKI (JP)
SHIRATORI YASUHIKO (JP)
HASEGAWA KIYOSHI (JP)
FUKAMI TAKAAKI (JP)
MIURA TAKAAKI (JP)
ONO NAOMI (JP)
YAMAZAKI TOSHIKAZU (JP)
NA YOUNG-JUN (KR)
YOON DONG-OH (KR)
KIM SUNG-JIN (KR)
Application Number:
PCT/JP2007/060666
Publication Date:
December 06, 2007
Filing Date:
May 25, 2007
Export Citation:
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Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
TSUKUDA TAKUO (JP)
KAWASAKI KEN-ICHI (JP)
KOMIYAMA SUSUMU (JP)
ISSHIKI YOSHIAKI (JP)
SHIRATORI YASUHIKO (JP)
HASEGAWA KIYOSHI (JP)
FUKAMI TAKAAKI (JP)
MIURA TAKAAKI (JP)
ONO NAOMI (JP)
YAMAZAKI TOSHIKAZU (JP)
NA YOUNG-JUN (KR)
YOON DONG-OH (KR)
KIM SUNG-JIN (KR)
International Classes:
C07D239/47; A61K31/505; A61K31/506; A61K31/53; A61K31/5377; A61P1/16; A61P3/04; A61P9/10; A61P11/00; A61P13/12; A61P17/00; A61P17/02; A61P19/02; A61P21/00; A61P25/00; A61P25/28; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07D251/16; C07D401/12; C07D403/10; C07D403/12; C07D405/04; C07D405/14; C07D413/14; C07D417/12; C07D417/14
Domestic Patent References:
WO2003037346A12003-05-08
WO2002036075A22002-05-10
WO2003037860A22003-05-08
WO2003055860A12003-07-10
WO2004050087A12004-06-17
WO2005021552A12005-03-10
WO2006122631A12006-11-23
WO2006123165A22006-11-23
WO2006008503A12006-01-26
WO2002036171A12002-05-10
WO2002009696A12002-02-07
WO1999051223A11999-10-14
WO2002002123A12002-01-10
WO2003037346A12003-05-08
WO2001027088A12001-04-19
Foreign References:
US20040204386A12004-10-14
JP2005225787A2005-08-25
JP2001505554A2001-04-24
JP2005225787A2005-08-25
US6210974B12001-04-03
JPS5170780A1976-06-18
US20040204386A12004-10-14
JPS60208968A1985-10-21
Other References:
DATABASE CAPLUS [online] DZIEWONSKI K. ET AL.: "Derivatives of napthalic acid. Synthesis of 3,4-dihydroxynaphthalic acid", XP003019815, accession no. STN Database accession no. (1932:57919)
FUTURE ONCOL., vol. 1, no. 4, 2005, pages 529 - 540
EXPERT OPIN. ON EMERGING DRUGS, vol. 10, no. 1, 2005, pages 137 - 149
CURR. CANCER DRUG TARGETS., vol. 3, no. 5, October 2003 (2003-10-01), pages 385 - 390
CHEM. BIOL., vol. 8, no. 3, March 2001 (2001-03-01), pages 289 - 299
JOURNAL FUER PRAKTISCHE CHEMIE (LEIPZIG, vol. 322, no. 1, 1980, pages 55 - 68
BIOORG. MED. CHEM. LETT., vol. 14, 2004, pages 2303 - 2308
NUCLEIC ACIDS RES., vol. 17, no. 17, 12 September 1989 (1989-09-12), pages 7108
JOURNAL OF THE NATIONAL CANCER INSTITUTE, vol. 81, no. 14, 19 July 1989 (1989-07-19), pages 1088 - 1092
See also references of EP 2036895A4
Attorney, Agent or Firm:
SHIMIZU, Hatsushi et al. (1-1-1 Oroshi-machi,Tsuchiura-sh, Ibaraki 47, JP)
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