Title:
HUMAN 7TM PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME
Document Type and Number:
WIPO Patent Application WO2002016435
Kind Code:
A3
Abstract:
The nucleotide and amino acid sequences of several novel human G protein coupled receptors are described.
Inventors:
HU YI
NEPOMNICHY BORIS
NEPOMNICHY BORIS
Application Number:
PCT/US2001/026643
Publication Date:
October 17, 2002
Filing Date:
August 21, 2001
Export Citation:
Assignee:
LEXICON GENETICS INC (US)
International Classes:
C07K14/705; C12N15/12; C12N15/09; (IPC1-7): C12N15/12; C12N15/11; C07K14/705; C07K16/28; C07H21/04; C12Q1/68; G01N33/53; G01N33/68
Domestic Patent References:
| WO2001098351A2 | 2001-12-27 |
Foreign References:
| US5688938A | 1997-11-18 |
Other References:
DATABASE EMBL [online] EMBL; 5 May 2000 (2000-05-05), NCI-CGAP: "hn57c05.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:3031976 3' similar to SW:CASR_BOVIN P35384 EXTRACELLULAR CALCIUM-SENSING RECEPTOR PRECURSOR ;, mRNA sequence.", XP002202812, Database accession no. AW771483
DATABASE EMBL [online] EMBL; 17 April 2000 (2000-04-17), WATERSTON R H: "Homo sapiens chromosome 6 clone RP11-259L5, WORKING DRAFT SEQUENCE, 5 unordered pieces.", XP002202813, Database accession no. AC053500
WILSON S ET AL.: "Orphan G-protein-coupled receptors: the next generation of drug targets?", BRITISH JOURNAL OF PHARMACOLOGY, vol. 125, no. 7, December 1998 (1998-12-01), pages 1387 - 1392, XP001010584, ISSN: 0007-1188
STADEL J M ET AL.: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 18, no. 11, 1 November 1997 (1997-11-01), pages 430 - 437, XP004099345, ISSN: 0165-6147
MARCHESE A ET AL.: "Discovery of three novel orphan G-protein-coupled receptors", GENOMICS, vol. 56, no. 1, 15 February 1999 (1999-02-15), pages 12 - 21, XP002108432, ISSN: 0888-7543
SONNHAMMER E L L ET AL.: "Pfam: a comprehensive database of protein domain families based on seed alignments.", PROTEINS, vol. 28, 1997, pages 405 - 420, XP002929239, ISSN: 0887-3585
TANABE Y ET AL.: "A family of metabotropic glutamate receptors", NEURON, vol. 8, no. 1, 1992, pages 169 - 179, XP000674842
DATABASE EMBL [online] EMBL; 6 May 2002 (2002-05-06), LORENZ-DEPIEREUX B ET AL.: "Homo sapiens G protein-coupled receptor, family C, group 6, member A (GPRC6A) mRNA, complete cds.", XP002202814, Database accession no. AF502962
DATABASE EMBL [online] EMBL; 17 April 2000 (2000-04-17), WATERSTON R H: "Homo sapiens chromosome 6 clone RP11-259L5, WORKING DRAFT SEQUENCE, 5 unordered pieces.", XP002202813, Database accession no. AC053500
WILSON S ET AL.: "Orphan G-protein-coupled receptors: the next generation of drug targets?", BRITISH JOURNAL OF PHARMACOLOGY, vol. 125, no. 7, December 1998 (1998-12-01), pages 1387 - 1392, XP001010584, ISSN: 0007-1188
STADEL J M ET AL.: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 18, no. 11, 1 November 1997 (1997-11-01), pages 430 - 437, XP004099345, ISSN: 0165-6147
MARCHESE A ET AL.: "Discovery of three novel orphan G-protein-coupled receptors", GENOMICS, vol. 56, no. 1, 15 February 1999 (1999-02-15), pages 12 - 21, XP002108432, ISSN: 0888-7543
SONNHAMMER E L L ET AL.: "Pfam: a comprehensive database of protein domain families based on seed alignments.", PROTEINS, vol. 28, 1997, pages 405 - 420, XP002929239, ISSN: 0887-3585
TANABE Y ET AL.: "A family of metabotropic glutamate receptors", NEURON, vol. 8, no. 1, 1992, pages 169 - 179, XP000674842
DATABASE EMBL [online] EMBL; 6 May 2002 (2002-05-06), LORENZ-DEPIEREUX B ET AL.: "Homo sapiens G protein-coupled receptor, family C, group 6, member A (GPRC6A) mRNA, complete cds.", XP002202814, Database accession no. AF502962
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