Title:
HUMAN BODY-INSERTABLE DILATOR USING HYDROGEL HAVING DUAL NETWORK STRUCTURE
Document Type and Number:
WIPO Patent Application WO/2021/096221
Kind Code:
A1
Abstract:
The present invention relates to a human body-insertable dilator using a hydrogel having a dual network structure and, more specifically, to a dilator comprising a hydrogel having a dual network structure, the hydrogel being composed of a biocompatible water-soluble or water-swellable polymer, and a biocompatible water-soluble or phase-transfer polymer. The present invention can provide a dilator comprising a hydrogel having a dual network structure, the dilator having a high expansion ratio, and having better mechanical strength, such as compressive strength and tensile strength, than laminaria and Dilapan-S. Particularly, the present invention can provide a biocompatible hydrogel having a dual network structure, the hydrogel having an excellent coefficient of moisture expansion, having a compressive strength of 30 MPa or more, which is at least twice as high as 16 MPa which is the maximum of a conventional product, and having a tensile strength which is at least 10 times as high as that of a conventional product. In addition, the present invention processes the hydrogel having a dual network structure so as to provide medical expansion rods, artificial joints, artificial ligaments, artificial muscles, scaffolds for tissue engineering, filler materials for plastic surgery/beauty treatment, culture gels for agriculture and gardening, and the like, which can be safely and quickly used without complications and side effects.
Inventors:
KIM SEONG CHEOL (KR)
KIM JA ROK (KR)
KIM JA ROK (KR)
Application Number:
PCT/KR2020/015793
Publication Date:
May 20, 2021
Filing Date:
November 11, 2020
Export Citation:
Assignee:
YEUNGNAM UNIV INDUSTRY ACADEMY (KR)
International Classes:
A61M29/02; A61B17/00; A61B17/42; A61B90/00; A61L31/04; A61L31/14
Foreign References:
| KR20190111011A | 2019-10-01 | |||
| KR20190060326A | 2019-06-03 | |||
| KR20100118860A | 2010-11-08 | |||
| KR20110062804A | 2011-06-10 |
Other References:
JING ZHANXIN, AIXING XU, YAN-QIU LIANG, ZHAOXIA ZHANG, CHUANMING YU, PENGZHI HONG, YONG LI: "Biodegradable Poly(acrylic acid-co-acrylamide)/Poly(vinyl alcohol) Double Network Hydrogels with Tunable Mechanics and High Self-healing Performance", POLYMERS, vol. 11, no. 6, 1 June 2019 (2019-06-01), XP055812324
Attorney, Agent or Firm:
PARK, Rho Choon (KR)
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