Title:
HUMAN CELLULAR MODELS WITH BIOSENSORS
Document Type and Number:
WIPO Patent Application WO/2015/034710
Kind Code:
A3
Abstract:
This invention provides biosensors, cell models, and methods of their use for monitoring ionic or voltage responses to contact with bioactive agents. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
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| WO/1997/038715 | NOVEL COMPOUNDS |
Inventors:
HUANG ANGELA L (US)
Application Number:
PCT/US2014/052717
Publication Date:
May 07, 2015
Filing Date:
August 26, 2014
Export Citation:
Assignee:
TEMPO BIOSCIENCE INC (US)
HUANG ANGELA L (US)
HUANG ANGELA L (US)
International Classes:
C07K1/00; G01N33/00; C07K5/00; C12N5/00; C12N15/00; C12P21/06
Foreign References:
| US20110154515A1 | 2011-06-23 | |||
| US20050101767A1 | 2005-05-12 | |||
| US20050196768A1 | 2005-09-08 | |||
| US20120115128A1 | 2012-05-10 | |||
| US20120258588A1 | 2012-10-11 |
Other References:
"Uniprot submission F6LWC2_XENLA, Voltage-Sensative Phosphase 2", 27 July 2011 (2011-07-27), XP055322947, Retrieved from the Internet [retrieved on 20150224]
Attorney, Agent or Firm:
BAKER, Gary et al. (P.C.P.O. Box 45, Alameda CA, US)
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