Title:
HUMAN STEM CELL PRESERVATIVE, HUMAN STEM CELL SUSPENSION, AND HUMAN STEM CELL PRESERVATION METHOD
Document Type and Number:
WIPO Patent Application WO/2018/147457
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a human stem cell preservative capable of preserving human stem cells at a high cell viability rate; a human stem cell suspension; and a human stem cell preservation method. According to the present invention, a human stem cell preservative for preserving human stem cells at a temperature greater than 0°C is provided, said preservative containing at least human blood serum, and having a human blood serum volume ratio of at least 0.70 with respect to the entire preservative.
Inventors:
YANADA SHINOBU (JP)
HADA SATOKO (JP)
SUZUKI KENTO (JP)
SEKIYA ICHIRO (JP)
MIZUNO MITSURU (JP)
KATANO HISAKO (JP)
OZEKI NOBUTAKE (JP)
OTABE KOUJI (JP)
HADA SATOKO (JP)
SUZUKI KENTO (JP)
SEKIYA ICHIRO (JP)
MIZUNO MITSURU (JP)
KATANO HISAKO (JP)
OZEKI NOBUTAKE (JP)
OTABE KOUJI (JP)
Application Number:
PCT/JP2018/004794
Publication Date:
August 16, 2018
Filing Date:
February 13, 2018
Export Citation:
Assignee:
FUJIFILM CORP (JP)
UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP)
UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP)
International Classes:
C12N5/074; C12N1/04
Foreign References:
| JPS4947948B1 | 1974-12-18 |
Other References:
MIZUNO, MICHIRU ET AL.: "Preservation by human serum maintains synovial membrane stem cell proliferation and cartilage differentiation ability", REGENERATIVE MEDICINE, vol. 16, no. Suppl. 2017, 1 February 2017 (2017-02-01), pages 277, XP009515807, ISSN: 1347-7919
SEKIYA, ICHIRO ET AL.: "Articular cartilage regeneration using synovial membrane stem cells", THE JOURNAL OF THERAPY, vol. 93, no. 8, 2011, pages 1784 - 1793, XP009515719, ISSN: 0022-5207
See also references of EP 3581644A4
SEKIYA, ICHIRO ET AL.: "Articular cartilage regeneration using synovial membrane stem cells", THE JOURNAL OF THERAPY, vol. 93, no. 8, 2011, pages 1784 - 1793, XP009515719, ISSN: 0022-5207
See also references of EP 3581644A4
Attorney, Agent or Firm:
SIKS & CO. (JP)
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