Title:
HUMAN WNT GENE
Document Type and Number:
WIPO Patent Application WO2001038353
Kind Code:
A3
Abstract:
The Wnt proteins are a family of secreted glycoproteins, which, in many organisms, have a role in the morphological development of tissues in both embryonic and adult contexts. The present invention provides a new form of human Wnt, designated "Zwnt3."
Inventors:
HOLLOWAY JAMES L
Application Number:
PCT/US2000/031820
Publication Date:
November 29, 2001
Filing Date:
November 17, 2000
Export Citation:
Assignee:
ZYMOGENETICS INC (US)
International Classes:
C07K14/47; A61K38/00; (IPC1-7): C12N15/12; C07K14/475; C07K16/22; C12Q1/68; G01N33/50
Other References:
SAITOH T ET AL: "MOLECULAR CLONING AND CHARACTERIZATION OF HUMAN WNT8A", INTERNATIONAL JOURNAL OF ONCOLOGY,EDITORIAL ACADEMY OF THE INTERNATIONAL JOURNAL OF ONCOLOGY,,GR, vol. 19, July 2001 (2001-07-01), pages 123 - 127, XP001014284, ISSN: 1019-6439
BOUILLET P ET AL: "A NEW MOUSE MEMBER OF THE WNT GENE FAMILY, MWNT-I, IS EXPRESSED DURING EARLY EMBRYOGENESIS AND IS ECTOPICALLY INDUCED BY RETINOIC ACID", MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE IRELAND LTD,IE, vol. 58, 1996, pages 141 - 152, XP001014150, ISSN: 0925-4773
CHRISTIAN J L ET AL: "XWNT-8, A XENOPUS WNT-1/INT-1-RELATED GENE RESPONSIVE TO MESODERM- INDUCING GROWTH FACTORS, MAY PLAY A ROLE IN VENTRAL MESODERMAL PATTERNING DURING EMBRYOGENESIS", DEVELOPMENT,COMPANY OF BIOLOGISTS, CAMBRIDGE,,GB, vol. 111, no. 4, 1991, pages 1045 - 1055, XP000566263, ISSN: 0950-1991
BOUILLET P ET AL: "A NEW MOUSE MEMBER OF THE WNT GENE FAMILY, MWNT-I, IS EXPRESSED DURING EARLY EMBRYOGENESIS AND IS ECTOPICALLY INDUCED BY RETINOIC ACID", MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE IRELAND LTD,IE, vol. 58, 1996, pages 141 - 152, XP001014150, ISSN: 0925-4773
CHRISTIAN J L ET AL: "XWNT-8, A XENOPUS WNT-1/INT-1-RELATED GENE RESPONSIVE TO MESODERM- INDUCING GROWTH FACTORS, MAY PLAY A ROLE IN VENTRAL MESODERMAL PATTERNING DURING EMBRYOGENESIS", DEVELOPMENT,COMPANY OF BIOLOGISTS, CAMBRIDGE,,GB, vol. 111, no. 4, 1991, pages 1045 - 1055, XP000566263, ISSN: 0950-1991
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