HUMANIZED ANTIBODY CAPABLE OF BINDING TO HEG1 PROTEIN, AND COMPLEX OF SAID ANTIBODY AND RADIOACTIVE NUCLEAR SPECIES

Title:

HUMANIZED ANTIBODY CAPABLE OF BINDING TO HEG1 PROTEIN, AND COMPLEX OF SAID ANTIBODY AND RADIOACTIVE NUCLEAR SPECIES

Document Type and Number:

WIPO Patent Application WO/2023/277144

Kind Code:

A1

Abstract:

The present invention provides: a humanized antibody capable of binding to HEG1 protein; and a complex of the antibody and a radioactive nuclear species. According to the present invention, a complex comprising an antibody and a radioactive nuclear species is provided, in which the antibody is a humanized antibody capable of binding to human HEG1 protein expressed in a mesothelioma cell.

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Inventors:

TAKEDA TAKUYA (JP)
KAWATANI MINORU (JP)
TONOYA GOTA (JP)
FUJIWARA KENTARO (JP)
TSUJI SHOUTARO (JP)

Application Number:

PCT/JP2022/026288

Publication Date:

January 05, 2023

Filing Date:

June 30, 2022

Export Citation:

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Assignee:

NIHON MEDIPHYSICS CO LTD (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)

International Classes:

C07K16/46; A61K39/395; A61K47/68; A61K51/10; A61P35/00; C12N15/13; A61K103/00; A61K103/40

Domestic Patent References:

WO2017141604A1	2017-08-24
WO2017217347A1	2017-12-21
WO2019203191A1	2019-10-24

Attorney, Agent or Firm:

MORITA Yutaka (JP)

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