Title:
HYBRID ALPHA-GLUCOSIDE TRANSPORTER
Document Type and Number:
WIPO Patent Application WO/2010/029610
Kind Code:
A1
Abstract:
An alpha-glucoside transporter which can quicken the metabolism of maltose-maltotriose contained in wort, etc. In particular, an alpha-glucoside transporter relating to the inactivation and degradation by glucose, which is scarcely inactivated or degraded by glucose owing to the hybridization of AGT1 with MAL21 and can intake maltotriose at a level comparable to AGT1. Use of, for example, a yeast expressing the alpha-glucoside transporter as described above makes it possible to quicken the fermentation speed of moromi mash containing oligosaccharides such as maltose-maltotriose.
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Inventors:
HATANAKA HARUYO (JP)
OMURA FUMIHIKO (JP)
OMURA FUMIHIKO (JP)
Application Number:
PCT/JP2008/066239
Publication Date:
March 18, 2010
Filing Date:
September 09, 2008
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
HATANAKA HARUYO (JP)
OMURA FUMIHIKO (JP)
HATANAKA HARUYO (JP)
OMURA FUMIHIKO (JP)
International Classes:
C12N15/00; C07K14/395; C12C11/00; C12G1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/00
Foreign References:
| JPH06245750A | 1994-09-06 |
Other References:
DIETVORST J. ET AL.: "Maltotriose utilization in lager yeast strains: MTT1 encodes a maltotriose transporter", YEAST, vol. 22, no. 10, 2005, pages 775 - 788, XP003026805
KODAMA Y. ET AL.: "Improvement of maltose fermentation efficiency: constitutive expression of MAL genes in brewing yeasts", J.AM.SOC.BREW.CHEM., vol. 53, no. 1, 1995, pages 24 - 29, XP002996798
MEDINTZ I. ET AL.: "A PEST-like sequence in the N-terminal cytoplasmic domain of Saccharomyces maltose permease is required for glucose-induced proteolysis and rapid inactivation of transport activity", BIOCHEMISTRY, vol. 39, no. 15, 2000, pages 4518 - 4526, XP008132899
GADURA N. ET AL.: "Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease are required for vacuolar degradation but not glucose-induced internalization", CURR. GENET., vol. 50, no. 2, 2006, pages 101 - 114, XP019423628
HAN E.K. ET AL.: "Characterization of AGT1 encoding a general a-glucoside transporter from Saccharomyces", MOL. MICROBIOL., vol. 17, no. 6, 1995, pages 1093 - 1107, XP003026803
See also references of EP 2189525A4
KODAMA Y. ET AL.: "Improvement of maltose fermentation efficiency: constitutive expression of MAL genes in brewing yeasts", J.AM.SOC.BREW.CHEM., vol. 53, no. 1, 1995, pages 24 - 29, XP002996798
MEDINTZ I. ET AL.: "A PEST-like sequence in the N-terminal cytoplasmic domain of Saccharomyces maltose permease is required for glucose-induced proteolysis and rapid inactivation of transport activity", BIOCHEMISTRY, vol. 39, no. 15, 2000, pages 4518 - 4526, XP008132899
GADURA N. ET AL.: "Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease are required for vacuolar degradation but not glucose-induced internalization", CURR. GENET., vol. 50, no. 2, 2006, pages 101 - 114, XP019423628
HAN E.K. ET AL.: "Characterization of AGT1 encoding a general a-glucoside transporter from Saccharomyces", MOL. MICROBIOL., vol. 17, no. 6, 1995, pages 1093 - 1107, XP003026803
See also references of EP 2189525A4
Attorney, Agent or Firm:
KOBAYASHI, Hiroshi et al. (JP)
Kobayashi 浩 (JP)
Kobayashi 浩 (JP)
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