Title:
HYBRID PROTEINS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/120542
Kind Code:
A8
Abstract:
There are disclosed hybrid proteins comprising at least one signal sequence; at least one DNA binding domain; and at least one cell penetrating peptide (CPP) domain. In embodiments the CPP domain is a TAT domain, and the DNA binding domain is a HU domain. There is also disclosed the use of the hybrid proteins to introduce exogenous DNA into target cells, and methods for introducing exogenous DNA into target cells using the hybrid proteins.
Inventors:
GRAVES HERBERT ALEXANDER (CA)
FOX MARK ANDREW (CA)
FOX MARK ANDREW (CA)
Application Number:
PCT/CA2015/000084
Publication Date:
October 27, 2016
Filing Date:
February 12, 2015
Export Citation:
Assignee:
SYMVIVO CORP (CA)
International Classes:
C07K19/00; C07K14/025; C07K14/16; C07K14/435; C12N1/21; C12N5/10; C12N15/62; C12N15/63; C12N15/85; C12N15/87; C12P21/02
Attorney, Agent or Firm:
SECHLEY, Konrad (550 Burrard Street Suite 2300, Bentall, Vancouver British Columbia V6C 2B5, CA)
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