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Title:
HYBRIDOMA CELL STRAIN SCCA1, MONOCLONAL ANTIBODY SECRETED THEREBY, AND APPLICATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2018/036435
Kind Code:
A1
Abstract:
A hybridoma cell strain SCCA1, a monoclonal antibody secreted thereby, and application of same. The collection number of the hybridoma cell strain SCCA1 is CCTCC No: C2016131. The monoclonal antibody is secreted by the hybridoma cell strain SCCA1, and may be used in the preparation of a reagent for detecting a cervical cancer. The monoclonal antibody is highly specific. An in vitro diagnostic kit for detecting the cervical cancer built on the basis of the monoclonal antibody has a high detection speed, uses only a small amount of blood sample, and provides highly sensitive detection results. The in vitro diagnostic kit provides a rapid, specific, and sensitive detecting method for different clinical and practical requirements, and greatly improves cervical cancer monitoring and management.

Inventors:
HUANG RUOPAN (CN)
LUO SHUHONG (CN)
FANG JIANMIN (CN)
ZHANG YUMING (CN)
HU YANG (CN)
Application Number:
PCT/CN2017/098110
Publication Date:
March 01, 2018
Filing Date:
August 18, 2017
Export Citation:
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Assignee:
RAYBIOTECH INC GUANGZHOU (CN)
International Classes:
C12N5/20; C07K16/30; G01N33/574; G01N33/577; C12R1/91
Foreign References:
CN106318912A2017-01-11
CN1684981A2005-10-19
Other References:
CATALTEPE, S.: "Co-expression of the Squamous Cell Carcinoma Antigens 1 and 2 in Normal Adult Human Tissues and Squamous Cell Carcinomas", THE JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1 January 2000 (2000-01-01), XP002974324
CATALTEPE, S.: "Development of specific monoclonal antibodies and a sensitive discriminatory immunoassay for the circulating tumor markers SCCA1 and SCCA2", CLINICA CHIMICA ACTA, vol. 295, no. 1-2, 31 May 2000 (2000-05-31), pages 107 - 127, XP002198888
ZHOU QIYANG ET AL.: "Evaluation of Clinical Diagnostic efficiency of self-made squamous cell carcinoma antigen monoclonal antibody chip", CHINESE JOURNAL OF MICROCIRCULATION, vol. 34, no. 4, 15 November 2013 (2013-11-15), pages 56 - 57
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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