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Patent Searching and Data


Title:
HYDRODYNAMICALLY CONTROLLED ELECTRIC FIELDS FOR HIGH THROUGHPUT TRANSFORMATION & HIGH THROUGHPUT PARALLEL TRANSFORMATION PLATFORM
Document Type and Number:
WIPO Patent Application WO/2017/210334
Kind Code:
A8
Abstract:
Methods and apparatuses for cell electroporation are provided. An apparatus includes a fluid transport structure, such as a pipette, that includes an electroporation structure defining a flow path having a constriction. The fluid transport structure also includes at least two conductive elements configured to produce an electric field in the flow path. The conductive elements are in operative arrangement with each other and are configured to expose cells contained within a cell suspension flowing through the fluid transport structure to an electric field that is sufficient to electroporate at least a subset of the cells in the flow path.

Inventors:
GARCIA DOMINGUEZ PAULO ANDRES (US)
GE ZHIFEI (US)
MCCORMACK RAMEECH N (US)
BUIE CULLEN RICHARD (US)
Application Number:
PCT/US2017/035270
Publication Date:
March 01, 2018
Filing Date:
May 31, 2017
Export Citation:
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Assignee:
MASSACHUSETTS INST TECHNOLOGY (US)
International Classes:
B01L3/02; C12M1/42; C12N13/00
Attorney, Agent or Firm:
SOLOMON, Mark, B. et al. (US)
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