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Title:
HYDROGEL-FORMING MATERIAL, PREMIX, AND HYDROGEL FORMATION METHOD
Document Type and Number:
WIPO Patent Application WO/2014/054702
Kind Code:
A1
Abstract:
[Problem] To provide a hydrogel-forming material, premix, and hydrogel formation method that make it possible to form hydrogel using a simpler method at milder temperature conditions (room temperature). [Solution] A hydrogel-forming material comprising: a dispersed phase (A) containing water, a fatty acid salt, and a lipid-peptide compound comprising a compound that is represented by formula (1) or at least one pharmaceutically usable salt of said compound; and a dispersed phase (B) of an acidic water-soluble polymer. (In the formula, R1 represents an aliphatic group having 9-23 carbon atoms, R2 represents an alkyl group that has 1-4 carbon atoms and that may have a branched chain of 1 or 2 hydrogen atoms or carbon atoms, R3 represents a -(CH2)n-X group, n represents a number between 1 and 4, and X represents a fused heterocyclic ring that is configured from a 5-membered ring, a 6-membered ring, or a 5-membered ring and a 6-membered ring that may have 1-3 amino groups, guanidino groups, -CONH2 groups, or nitrogen atoms.)

Inventors:
MATSUMOTO KEIGO (JP)
KASHINO TSUBASA (JP)
Application Number:
PCT/JP2013/076843
Publication Date:
April 10, 2014
Filing Date:
October 02, 2013
Export Citation:
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Assignee:
NISSAN CHEMICAL IND LTD (JP)
International Classes:
A61K9/06; A61K8/36; A61K8/64; A61K8/81; A61K47/10; A61K47/12; A61K47/32; A61K47/42
Domestic Patent References:
WO2010106981A12010-09-23
WO2012063947A12012-05-18
WO2011052613A12011-05-05
WO2012144609A12012-10-26
WO2012133787A12012-10-04
WO2009005151A12009-01-08
WO2009005152A12009-01-08
Foreign References:
JPH0853693A1996-02-27
Other References:
SUZUKI, MASAHIRO; YUMOTO, MARIKO. MUTSUMI; SHIRAI. HIROFUSA; HANABUSA, KENJI, CHEMISTRY LETTERS, vol. 33, no. 11, pages 1496 - 1497
JONG HWA JUNG; GEOREG JOHN; MITSUTOSISH MAUSDA; KANAME YOSHIDA; SEIJI SHINNKAI; TOSHIMI SHIMIZU, LANGUMIR, vol. 17, 2001, pages 7229 - 7232
I. HAMACHI; S. KIYONAKA; S. SHINKAI, TETRAHEDRON LETT., vol. 42, 2001, pages 6141
I. HAMACHI; S. KIYONAKA; S. SHINAKI, CHEM. COMMUN., 2000, pages 1281
MASAHIRO SUZUKI; SANAE OWA; HIROFUSA SHIRAI; KENJI HANABUSA, TETRAHEDRON, vol. 63, 2007, pages 7302 - 7308
YOKO MATSUZAWA; KATSUYUKI UEKI; MASARU YOSHIDA; NOBUYUKI TAMAOKI; TOHRU NAKAMURA; HIDEKI SAKAI; MASAHIKO ABE, ADV. FUNCT. MATER., vol. 17, 2007, pages 1507 - 1514
See also references of EP 2905015A4
Attorney, Agent or Firm:
HANABUSA, Tsuneo et al. (JP)
Sepal Tsuneo (JP)
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