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Title:
HYDROGEL OF POLYSACCHARIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2010/095304
Kind Code:
A1
Abstract:
An impaired nervous function repairing agent including a hydrogel of a polysaccharide derivative that has a complex elastic modulus 1 to 1000 N/m2 and a loss coefficient of 0.01 to 2.0 calculated at an angular velocity of 10 rad/sec using a dynamic viscoelasticity measuring device filled with a 0.5 wt% aqueous solution. The impaired nervous function repairing agent is available in a form of a hydrogel capable of being injected with an injector, has excellent retentivity inside the body, and is effective at recovering a damaged or degenerated nervous function.

Inventors:
ENDO NOBUYUKI (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
Application Number:
PCT/JP2009/066858
Publication Date:
August 26, 2010
Filing Date:
September 18, 2009
Export Citation:
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Assignee:
TEIJIN LTD (JP)
UNIV NAGOYA NAT UNIVERSITY COR (JP)
ENDO NOBUYUKI (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
International Classes:
A61K31/715; A61K31/717; A61L31/00; A61P25/00; A61P25/02; A61P41/00; C08B15/05
Domestic Patent References:
WO2007015579A12007-02-08
WO2007015579A12007-02-08
Foreign References:
JP2000198738A2000-07-18
JPH0930979A1997-02-04
JPH06157338A1994-06-03
JPH0930979A1997-02-04
JP2000198738A2000-07-18
Other References:
THE BRITISH ASSOCIATION OF PLASTIC SURGEONS, vol. 56, 2003, pages 342 - 347
MICROSURGERY, vol. 27, no. 1, 2007, pages 2 - 7
HIDEHIKO OHSUMI, HITOSHI HIRATA, TAKESHI NAGAKURA, MASAYA TSUJII, TOSHIKO SUGIMOTO, KEIICHI MIYAMOTO, TAKESHI HORIUCHI, PLASTIC AND RECONSTRUCTIVE SURGERY, vol. 116, no. 3, 2005, pages 823 - 30
Attorney, Agent or Firm:
MIHARA, Hideko (JP)
Hideko Mihara (JP)
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