Title:
HYDROGEL OF POLYSACCHARIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2010/095304
Kind Code:
A1
Abstract:
An impaired nervous function repairing agent including a hydrogel of a polysaccharide derivative that has a complex elastic modulus 1 to 1000 N/m2 and a loss coefficient of 0.01 to 2.0 calculated at an angular velocity of 10 rad/sec using a dynamic viscoelasticity measuring device filled with a 0.5 wt% aqueous solution. The impaired nervous function repairing agent is available in a form of a hydrogel capable of being injected with an injector, has excellent retentivity inside the body, and is effective at recovering a damaged or degenerated nervous function.
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Inventors:
ENDO NOBUYUKI (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
Application Number:
PCT/JP2009/066858
Publication Date:
August 26, 2010
Filing Date:
September 18, 2009
Export Citation:
Assignee:
TEIJIN LTD (JP)
UNIV NAGOYA NAT UNIVERSITY COR (JP)
ENDO NOBUYUKI (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
UNIV NAGOYA NAT UNIVERSITY COR (JP)
ENDO NOBUYUKI (JP)
ITO MASAYA (JP)
KANEKO HIROAKI (JP)
HIRATA HITOSHI (JP)
YAMAMOTO MICHIRO (JP)
International Classes:
A61K31/715; A61K31/717; A61L31/00; A61P25/00; A61P25/02; A61P41/00; C08B15/05
Domestic Patent References:
WO2007015579A1 | 2007-02-08 | |||
WO2007015579A1 | 2007-02-08 |
Foreign References:
JP2000198738A | 2000-07-18 | |||
JPH0930979A | 1997-02-04 | |||
JPH06157338A | 1994-06-03 | |||
JPH0930979A | 1997-02-04 | |||
JP2000198738A | 2000-07-18 |
Other References:
THE BRITISH ASSOCIATION OF PLASTIC SURGEONS, vol. 56, 2003, pages 342 - 347
MICROSURGERY, vol. 27, no. 1, 2007, pages 2 - 7
HIDEHIKO OHSUMI, HITOSHI HIRATA, TAKESHI NAGAKURA, MASAYA TSUJII, TOSHIKO SUGIMOTO, KEIICHI MIYAMOTO, TAKESHI HORIUCHI, PLASTIC AND RECONSTRUCTIVE SURGERY, vol. 116, no. 3, 2005, pages 823 - 30
MICROSURGERY, vol. 27, no. 1, 2007, pages 2 - 7
HIDEHIKO OHSUMI, HITOSHI HIRATA, TAKESHI NAGAKURA, MASAYA TSUJII, TOSHIKO SUGIMOTO, KEIICHI MIYAMOTO, TAKESHI HORIUCHI, PLASTIC AND RECONSTRUCTIVE SURGERY, vol. 116, no. 3, 2005, pages 823 - 30
Attorney, Agent or Firm:
MIHARA, Hideko (JP)
Hideko Mihara (JP)
Hideko Mihara (JP)
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