Title:
HYDROPHILIC-HYDROPHOBIC COPOLYMER CARRYING SHORT-CHAIN FATTY ACID ESTER
Document Type and Number:
WIPO Patent Application WO/2021/024906
Kind Code:
A1
Abstract:
[Problem] To provide a short-chain fatty acid derivative capable of performing a physiological function inherent to a short chain fatty acid. [Solution] Provided is a block or graft copolymer containing: a hydrophobic segment having a repeating unit including a short-chain fatty acid that can be hydrolyzed by an esterase in vivo; and a hydrophilic segment including a poly(ethylene glycol) chain. This copolymer is effective in treating or therapeutically treating various diseases or disorders including cancer.
Inventors:
NAGASAKI YUKIO (JP)
SHASHNI BABITA (JP)
VONG BINH LONG (JP)
OKADA RYUSAKU (JP)
TAJIKA YUYA (JP)
LEE YAROSLAV (JP)
SHASHNI BABITA (JP)
VONG BINH LONG (JP)
OKADA RYUSAKU (JP)
TAJIKA YUYA (JP)
LEE YAROSLAV (JP)
Application Number:
PCT/JP2020/029239
Publication Date:
February 11, 2021
Filing Date:
July 30, 2020
Export Citation:
Assignee:
UNIV TSUKUBA (JP)
International Classes:
A61P1/04; A61K31/19; A61K47/60; A61P1/16; A61P3/04; A61P35/00; C08F8/14; C08F290/06; C08F293/00; C08G65/334
Domestic Patent References:
| WO2018135592A1 | 2018-07-26 | |||
| WO2019208617A1 | 2019-10-31 | |||
| WO2009133647A1 | 2009-11-05 | |||
| WO2016052463A1 | 2016-04-07 |
Foreign References:
| JPH0616752A | 1994-01-25 | |||
| JPH0616747A | 1994-01-25 | |||
| JP2007185494A | 2007-07-26 | |||
| JP2019001786A | 2019-01-10 |
Other References:
TAKASHI SAKATAHIROHUMI ICHIKAWA: "Physiological Actions of Short-Chain Fatty Acids", JOURNAL OF JAPAN OIL CHEMISTS' SOCIETY, vol. 46, 1997, pages 1205 - 1212
Attorney, Agent or Firm:
PATENT PROFESSION CORPORATION ODAJIMA PATENT OFFICE (JP)
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