HYDROPHILIC MATERIAL, MEDICAL MATERIAL AND SUSTAINED RELEASE PHARMACEUTICAL MATERIAL

WIPO Patent Application WO/2010/038747

A1

A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the β-position of an α,β-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the α,β-unsaturated carboxyl group and one or more hydroxyl groups.  In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained release pharmaceutical material.

AKASHI MITSURU (JP)
MATSUSAKI MICHIYA (JP)
SHI DONGJIAN (JP)
ONISHI MAKOTO (JP)
FUJITA YOTARO (JP)

PCT/JP2009/066966

April 08, 2010

September 29, 2009

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UNIV OSAKA (JP)
TERUMO CORP (JP)
AKASHI MITSURU (JP)
MATSUSAKI MICHIYA (JP)
SHI DONGJIAN (JP)
ONISHI MAKOTO (JP)
FUJITA YOTARO (JP)

C08G63/91; A61K9/14; A61K47/34; C08G81/00

WO2009054113A1

2009-04-30

US4053415A	1977-10-11
US4355136A	1982-10-19
EP1873183A1	2008-01-02
JPS5021804A	1975-03-08
JPH1160928A	1999-03-05
JPS60110722A	1985-06-17
JP2004250700A	2004-09-09

MITSURU AKASHI: "KOBUNSHI", vol. 55, 2006, THE ORGAN OF THE SOCIETY OF POLYMER SCIENCE, article "Kankyojunkan- gata Enjiniaringupurasuchikku", pages: 870 - 873
See also references of EP 2336218A4

WATANABE Mochitoshi et al. (JP)
Mochitoshi Watanabe (JP)

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