Title:
HYDROXYMETHYL PIPERIDINE OREXIN RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/2016/086358
Kind Code:
A1
Abstract:
Provided are hydroxymethyl piperidine compounds, which are antagonists of orexin receptors, and compositions thereof. Provided are also methods for treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.
Inventors:
KUDUK SCOTT D (US)
LIVERTON NIGEL (US)
LUO YUNFU (CN)
LIVERTON NIGEL (US)
LUO YUNFU (CN)
Application Number:
PCT/CN2014/092805
Publication Date:
June 09, 2016
Filing Date:
December 02, 2014
Export Citation:
Assignee:
MERCK SHARP & DOHME (US)
KUDUK SCOTT D (US)
LIVERTON NIGEL (US)
LUO YUNFU (CN)
KUDUK SCOTT D (US)
LIVERTON NIGEL (US)
LUO YUNFU (CN)
International Classes:
C07D401/02; A61K31/4545; A61P25/00; C07D211/06; C07D401/14
Domestic Patent References:
WO2014176146A1 | 2014-10-30 | |||
WO2010048012A1 | 2010-04-29 | |||
WO2014062533A1 | 2014-04-24 | |||
WO2014066196A1 | 2014-05-01 | |||
WO2013059222A1 | 2013-04-25 | |||
WO2014099696A1 | 2014-06-26 | |||
WO2014099698A1 | 2014-06-26 | |||
WO2014099697A1 | 2014-06-26 | |||
WO2013062857A1 | 2013-05-02 |
Attorney, Agent or Firm:
WU, FENG & ZHANG CO. (Tower B,Beijing Aerospace Cpmiec Building,No. 30, Haidian South Road, Haidian District, Beijing 0, CN)
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