Title:
HYPERTHERMIC THERAPY KIT FOR MALIGNANT TUMOR COMPRISING ANTI-REGULATORY-T-CELL ANTIBODY AND MAGNETIC MICROPARTICLE, AND HYPERTHERMIC THERAPY USING THE KIT
Document Type and Number:
WIPO Patent Application WO/2010/026638
Kind Code:
A1
Abstract:
Disclosed are: a kit for the hyperthermic therapy for a malignant tumor, which comprises a substance comprising an anti-regulatory-T-cell antibody and a substance comprising a magnetic microparticle; and a hyperthermic therapy using the kit.
Inventors:
KOBAYASHI TAKESHI
MORINO TOMIO
MORINO TOMIO
Application Number:
PCT/JP2008/065983
Publication Date:
March 11, 2010
Filing Date:
September 04, 2008
Export Citation:
Assignee:
KOBAYASHI TAKESHI
NANOTHERAPY CO LTD (JP)
MORINO TOMIO
NANOTHERAPY CO LTD (JP)
MORINO TOMIO
International Classes:
A61K39/395; A61K33/26; A61P35/00
Domestic Patent References:
| WO1997027876A1 | 1997-08-07 |
Foreign References:
| JPH03128331A | 1991-05-31 | |||
| JP2006306824A | 2006-11-09 |
Other References:
MELERO I. ET AL.: "Immunostimulatory monoclonal antibodies for cancer therapy", NAT REV CANCER, vol. 7, no. 2, 2007, pages 95 - 106
YANASE M. ET AL.: "Antitumor immunity induction by intracellular hyperthermia using magnetite cationic liposomes", JPN. J. CANCER RES., vol. 89, 1998, pages 775 - 782
ADACHI,S. ET AL.: "Hyperthermia cancels tumor- associated immune suppression", GASTROENTEROLOGY, vol. 134, no. 4, 2008, pages A748
YANASE M. ET AL.: "Antitumor immunity induction by intracellular hyperthermia using magnetite cationic liposomes", JPN. J. CANCER RES., vol. 89, 1998, pages 775 - 782
ADACHI,S. ET AL.: "Hyperthermia cancels tumor- associated immune suppression", GASTROENTEROLOGY, vol. 134, no. 4, 2008, pages A748
Attorney, Agent or Firm:
TSUKUNI, HAJIME (JP)
Hajime Tsukuni (JP)
Hajime Tsukuni (JP)
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