Title:
IMMUNE CELL INDUCED FROM iPS CELL
Document Type and Number:
WIPO Patent Application WO/2024/071411
Kind Code:
A1
Abstract:
[Problem] To provide an immune cell induced from an iPS cell, to which a phenotype favorable to the migration or invasion of an immune cell to a solid tumor site and the proliferation and survive of an immune cell in a solid tumor is imparted. [Solution] Provided is an immune cell which is induced from an iPS cell and is capable of expressing interleukin 15 and a cell surface molecule having reactivity with a tumor-related antigen. Also provided is an immune cell which is induced from an iPS cell and is capable of expressing interleukin 12, interleukin 18 or interleukin 21 and a cell surface molecule having reactivity with a tumor-related antigen.
Inventors:
KANEKO SHIN (JP)
ISHIKAWA AKIHIRO (JP)
KANIE KEITARO (JP)
ISHIKAWA AKIHIRO (JP)
KANIE KEITARO (JP)
Application Number:
PCT/JP2023/035752
Publication Date:
April 04, 2024
Filing Date:
September 29, 2023
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
C12N5/10; A61K35/17; A61P35/00; C12N5/0783; C12N15/12; C12N15/24; C12N15/62; C12N15/85
Attorney, Agent or Firm:
SHA PATENT AND TRADEMARK FIRM (JP)
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