Title:
ISOCARBACYCLIN WITH MODIFIED alpha-CHAIN AND PROCESS FOR PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/1994/007838
Kind Code:
A1
Abstract:
An isocarbacyclin with the alpha-chain modified with phenylene, cycloalkylene or thiophenediyl. It has the activity of inhibiting DNA synthesis of human smooth muscle cells and is expected to inhibit vascular hypertrophy.
Inventors:
KOGA MASAHIRO (JP)
TANAKA TOSHIO (JP)
FUJII TAKAO (JP)
MASEGI TSUKIO (JP)
TANAKA TOSHIO (JP)
FUJII TAKAO (JP)
MASEGI TSUKIO (JP)
Application Number:
PCT/JP1993/001407
Publication Date:
April 14, 1994
Filing Date:
October 01, 1993
Export Citation:
Assignee:
TEIJIN LTD (JP)
KOGA MASAHIRO (JP)
TANAKA TOSHIO (JP)
FUJII TAKAO (JP)
MASEGI TSUKIO (JP)
KOGA MASAHIRO (JP)
TANAKA TOSHIO (JP)
FUJII TAKAO (JP)
MASEGI TSUKIO (JP)
International Classes:
C07C65/19; C07C69/76; C07C405/00; (IPC1-7): C07C61/35; C07C69/76; C07C67/343
Foreign References:
| JPS56138130A | 1981-10-28 | |||
| JPS59500767A | 1984-05-04 | |||
| JPS63303956A | 1988-12-12 | |||
| JPS62258330A | 1987-11-10 | |||
| JPH06261937A | 1994-09-20 |
Other References:
See also references of EP 0664281A4
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