Title:
IDENTIFICATION OF BROADLY REACTIVE HLA RESTRICTED T CELL EPITOPES
Document Type and Number:
WIPO Patent Application WO2000044775
Kind Code:
A3
Abstract:
This application discloses five new amino acid supermotifs and corresponding grouping of HLA molecules (i.e., HLA supertypes that bind peptides that bear these supermotifs). Peptides epitopes bearing these supermotifs are selected for use in vaccines and other pharmaceutical compositions. The new supermotifs are used to screen known disease-related targets, as well as targets that will be determined in the future.
Inventors:
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
SIDNEY JOHN (US)
Application Number:
PCT/US2000/001918
Publication Date:
November 30, 2000
Filing Date:
January 26, 2000
Export Citation:
Assignee:
EPIMMUNE INC (US)
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
International Classes:
C07K14/74; G01N33/68; (IPC1-7): C07K14/00; C07K14/705; G01N33/68
Domestic Patent References:
| WO1997033602A1 | 1997-09-18 | |||
| WO1996003140A1 | 1996-02-08 | |||
| WO1997035035A1 | 1997-09-25 |
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