Title:
IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
Document Type and Number:
WIPO Patent Application WO2008054603
Kind Code:
A9
Abstract:
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
Inventors:
TOCKER JOEL (US)
PESCHON JACQUES J (US)
FITZPATRICK DAVID (US)
SMOTHERS JAMES F (US)
MEHLIN CHRISTOPHER (US)
LIM AI CHING (US)
PESCHON JACQUES J (US)
FITZPATRICK DAVID (US)
SMOTHERS JAMES F (US)
MEHLIN CHRISTOPHER (US)
LIM AI CHING (US)
Application Number:
PCT/US2007/021174
Publication Date:
July 03, 2008
Filing Date:
October 01, 2007
Export Citation:
Assignee:
AMGEN INC (US)
TOCKER JOEL (US)
PESCHON JACQUES J (US)
FITZPATRICK DAVID (US)
SMOTHERS JAMES F (US)
MEHLIN CHRISTOPHER (US)
LIM AI CHING (US)
TOCKER JOEL (US)
PESCHON JACQUES J (US)
FITZPATRICK DAVID (US)
SMOTHERS JAMES F (US)
MEHLIN CHRISTOPHER (US)
LIM AI CHING (US)
International Classes:
C07K16/00
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