Title:
IL-17A CONJUGATE AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/070697
Kind Code:
A1
Abstract:
Provided is an antibody capable of specially recognizing IL-17A and being combined with IL-17A. The antibody can be used for treating inflammations and autoimmune diseases caused by high expression of interleukin-17A, such as psoriasis, psoriatic arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory arthritis.
Inventors:
ZHANG LIANSHAN (CN)
LIU JIAJIAN (CN)
CAO GUOQING (CN)
SUN PIAOYANG (CN)
LIU JIAJIAN (CN)
CAO GUOQING (CN)
SUN PIAOYANG (CN)
Application Number:
PCT/CN2014/089542
Publication Date:
May 21, 2015
Filing Date:
October 27, 2014
Export Citation:
Assignee:
SHANGHAI HENGRUI PHARM CO LTD (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
International Classes:
C07K16/24; A61K39/395; A61P19/02; A61P37/02; C12N15/13; C12N15/63
Domestic Patent References:
| WO2010034443A1 | 2010-04-01 |
Foreign References:
| CN101001645A | 2007-07-18 | |||
| CN101326195A | 2008-12-17 | |||
| CN101646690A | 2010-02-10 | |||
| US7838638B2 | 2010-11-23 | |||
| US7807155B2 | 2010-10-05 |
Other References:
DATABASE GENBANK [online] 15 September 2005 (2005-09-15), "IMMUNOGLOBULIN HEAVY CHAIN VDJ REGION, PARTIAL [MUS MUSCULUS]", XP055343971, retrieved from NCBI ncbi Database accession no. AA059842
AGGARWAL ET AL., J.LEUKOC.BIOL, vol. 71, no. 1, 2002, pages 1 - 8
SPRIGGS ET AL., J.CLIN.IMMUNOL, vol. 17, 1997, pages 366 - 369
KOLLS ET AL., IMMUNITY, vol. 21, 2004, pages 467 - 476
KAWAGUCHI ET AL., J.ALLERGY CLIN.IMMUNOL, vol. 114, no. 6, 2004, pages 1267 - 1273
MOSELEY ET AL., CYTOKINE GROWTH FACTOR REV, vol. 14, no. 2, 2003, pages 155 - 174
J. BIOL. CHEM, vol. 243, 1968, pages 3558
SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", COLD SPRING HARBOR LABORATORY
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", GREENE PUBLISHING ASSOCIATES, WILEY INTERSCIENCE
AGGARWAL ET AL., J.LEUKOC.BIOL, vol. 71, no. 1, 2002, pages 1 - 8
SPRIGGS ET AL., J.CLIN.IMMUNOL, vol. 17, 1997, pages 366 - 369
KOLLS ET AL., IMMUNITY, vol. 21, 2004, pages 467 - 476
KAWAGUCHI ET AL., J.ALLERGY CLIN.IMMUNOL, vol. 114, no. 6, 2004, pages 1267 - 1273
MOSELEY ET AL., CYTOKINE GROWTH FACTOR REV, vol. 14, no. 2, 2003, pages 155 - 174
J. BIOL. CHEM, vol. 243, 1968, pages 3558
SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", COLD SPRING HARBOR LABORATORY
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", GREENE PUBLISHING ASSOCIATES, WILEY INTERSCIENCE
Attorney, Agent or Firm:
GE CHENG & CO. LTD (CN)
北京戈程知识产权代理有限公司 (CN)
北京戈程知识产权代理有限公司 (CN)
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