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Title:
IL-33 ANTAGONIST-CONTAINING THERAPEUTIC AGENT FOR ENDOMETRIOSIS
Document Type and Number:
WIPO Patent Application WO/2019/045075
Kind Code:
A1
Abstract:
To provide a therapeutic agent for endometriosis and adenomyosis. IL-33 was identified as an exacerbating factor in endometriosis and adenomyosis, and an IL-33 antagonist, which is capable of inhibiting the function of IL-33, was found to be useful for treating, preventing or alleviating endometriosis and uterine adenomyosis.

Inventors:
YOSHIMOTO TOMOHIRO (JP)
PALUMBO M JOSEPH (US)
STONE I VIOLETTA (US)
KATO TORU (JP)
YASUDA KOUBUN (JP)
Application Number:
JP2018/032494
Publication Date:
March 07, 2019
Filing Date:
August 31, 2018
Export Citation:
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Assignee:
MITSUBISHI TANABE PHARMA CORP (JP)
HYOGO COLLEGE MEDICINE (JP)
International Classes:
A61K45/00; A61K38/17; A61K39/395; A61K47/68; A61P15/00; C07K16/24; C07K19/00; C12N15/113
Domestic Patent References:
WO2016140921A12016-09-09
WO2016077366A12016-05-19
WO2017062456A22017-04-13
WO2016140921A12016-09-09
WO2014164959A22014-10-09
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Foreign References:
EP0125023A11984-11-14
Other References:
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Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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