Title:
IL-8 LIKE PROTEIN
Document Type and Number:
WIPO Patent Application WO2004024762
Kind Code:
A3
Abstract:
This invention relates to a novel protein, termed INSP089, herein identified as an IL-8 like protein and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention and treatment of disease.
Inventors:
FAGAN RICHARD JOSEPH (GB)
PHELPS CHRISTOPHER BENJAMIN (GB)
DAVIES MARK DOUGLAS (GB)
POWER CHRISTINE (FR)
PHELPS CHRISTOPHER BENJAMIN (GB)
DAVIES MARK DOUGLAS (GB)
POWER CHRISTINE (FR)
Application Number:
PCT/GB2003/003957
Publication Date:
May 27, 2004
Filing Date:
September 12, 2003
Export Citation:
Assignee:
ARES TRADING SA (CH)
FAGAN RICHARD JOSEPH (GB)
PHELPS CHRISTOPHER BENJAMIN (GB)
DAVIES MARK DOUGLAS (GB)
POWER CHRISTINE (FR)
FAGAN RICHARD JOSEPH (GB)
PHELPS CHRISTOPHER BENJAMIN (GB)
DAVIES MARK DOUGLAS (GB)
POWER CHRISTINE (FR)
International Classes:
C07K14/52; C07K14/54; C12N15/19; C12N15/24; (IPC1-7): C07K14/54; A61K38/19; A61K38/20; A61K39/00; C07K14/52; C12N5/10; C12N15/19; C12N15/24; C12Q1/68; G01N33/50
Other References:
OPPENHEIM J J ET AL: "PROPERTIES OF THE NOVEL PROINFLAMMATORY SUPERGENE INTERCRINE CYTOKINE FAMILY", ANNUAL REVIEW OF IMMUNOLOGY, ANNUAL REVIEWS INC, US, vol. 9, 1991, pages 617 - 648, XP000926599, ISSN: 0732-0582
AN PING ET AL: "Modulating influence on HIV/AIDS by interacting RANTES gene variants", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 99, no. 15, 23 July 2002 (2002-07-23), July 23, 2002, pages 10002 - 10007, XP002272383, ISSN: 0027-8424
DATABASE SWISSPROT [online] EBI; 1 January 1990 (1990-01-01), "SY05 human", XP002272386, Database accession no. P13501
DATABASE EMBL [online] EBI; 25 July 2001 (2001-07-25), "homo sapiens BAC clone RP11-225M4", XP002272387, Database accession no. AC092619
HORIGUCHI HYOGO ET AL: "Cadmium-induced acute hepatic injury is exacerbated in human interleukin-8 transgenic mice", TOXICOLOGY AND APPLIED PHARMACOLOGY, vol. 163, no. 3, 15 March 2000 (2000-03-15), pages 231 - 239, XP002272384, ISSN: 0041-008X
NOMIYAMA H ET AL: "Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, HCC-1, LEC and RANTES", JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 19, 1999, pages 227 - 234, XP002965394, ISSN: 1079-9907
MICHALOVICH DAVID ET AL: "Protein sequence analysis in silico: Application of structure-based bioinformatics to genomic initiatives", CURRENT OPINION IN PHARMACOLOGY, vol. 2, no. 5, October 2002 (2002-10-01), pages 1 - 7, XP002272385, ISSN: 1471-4892
DATABASE SWISSPROT [online] ebi; 1 May 2000 (2000-05-01), ADAMS ET AL.,: "cG9129 protein of drosophila melanogaster", XP002272388, Database accession no. Q9W0I5
AN PING ET AL: "Modulating influence on HIV/AIDS by interacting RANTES gene variants", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 99, no. 15, 23 July 2002 (2002-07-23), July 23, 2002, pages 10002 - 10007, XP002272383, ISSN: 0027-8424
DATABASE SWISSPROT [online] EBI; 1 January 1990 (1990-01-01), "SY05 human", XP002272386, Database accession no. P13501
DATABASE EMBL [online] EBI; 25 July 2001 (2001-07-25), "homo sapiens BAC clone RP11-225M4", XP002272387, Database accession no. AC092619
HORIGUCHI HYOGO ET AL: "Cadmium-induced acute hepatic injury is exacerbated in human interleukin-8 transgenic mice", TOXICOLOGY AND APPLIED PHARMACOLOGY, vol. 163, no. 3, 15 March 2000 (2000-03-15), pages 231 - 239, XP002272384, ISSN: 0041-008X
NOMIYAMA H ET AL: "Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, HCC-1, LEC and RANTES", JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 19, 1999, pages 227 - 234, XP002965394, ISSN: 1079-9907
MICHALOVICH DAVID ET AL: "Protein sequence analysis in silico: Application of structure-based bioinformatics to genomic initiatives", CURRENT OPINION IN PHARMACOLOGY, vol. 2, no. 5, October 2002 (2002-10-01), pages 1 - 7, XP002272385, ISSN: 1471-4892
DATABASE SWISSPROT [online] ebi; 1 May 2000 (2000-05-01), ADAMS ET AL.,: "cG9129 protein of drosophila melanogaster", XP002272388, Database accession no. Q9W0I5
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