Title:
IL-8 RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO2001068570
Kind Code:
A3
Abstract:
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
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Inventors:
WIDDOWSON KATHERINE L (US)
JIN QI (US)
JIN QI (US)
Application Number:
PCT/US2001/008187
Publication Date:
April 18, 2002
Filing Date:
March 14, 2001
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORP (US)
WIDDOWSON KATHERINE L (US)
JIN QI (US)
WIDDOWSON KATHERINE L (US)
JIN QI (US)
International Classes:
A61K31/18; A61K31/198; A61K31/216; A61P1/02; A61P1/04; A61P1/16; A61P1/00; A61P1/18; A61P7/00; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/02; A61P11/06; A61P11/08; A61P11/14; A61P11/16; A61P13/12; A61P15/06; A61P17/00; A61P17/02; A61P17/06; A61P17/08; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P25/00; A61P25/22; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P31/14; A61P31/20; A61P31/22; A61P33/06; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07C311/47; (IPC1-7): A61K31/18; A61K31/196; A61K31/216; A61K31/222; A61K31/277; C07C311/47
Domestic Patent References:
| WO1997049680A1 | 1997-12-31 | |||
| WO1997049286A1 | 1997-12-31 |
Other References:
DATABASE CAPLUS [online] CHEM. ABSTR., (COLUMBUS, OHIO, USA); KALCHEVA V. ET AL.: "Synthesis of 1-(2-hydroxyaryl)- and 1-methyl-1-(2-hydroxyaryl)-3-N-butylureas", XP002947189, accession no. STN Database accession no. 1989:38704
DATABASE CAPLUS [online] CHEM. ABSTR., (COLUMBUS, OHIO, USA); LOZANOVA KH.S. ET AL.: "Synthesis and biological activity of 1-(2-hydroxyaryl)-3-benzyl- and 1-(2-hydroxyaryl)-3-pyrrolidinylureas", XP002947188, accession no. STN Database accession no. 1992:426229
DATABASE CAPLUS [online] CHEM. ABSTR., (COLUMBUS, OHIO, USA); LOZANOVA KH.S. ET AL.: "Synthesis and biological activity of 1-(2-hydroxyaryl)-3-benzyl- and 1-(2-hydroxyaryl)-3-pyrrolidinylureas", XP002947188, accession no. STN Database accession no. 1992:426229
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