IMAGE DIAGNOSIS PROBE BASED ON SUBSTITUTED AZOBENZENE OR ANALOGUE THEREOF FOR DISEASE ATTRIBUTABLE TO AMYLOID ACCUMULATION AND COMPOSITION FOR IMAGE DIAGNOSIS CONTAINING THE SAME

Title:

IMAGE DIAGNOSIS PROBE BASED ON SUBSTITUTED AZOBENZENE OR ANALOGUE THEREOF FOR DISEASE ATTRIBUTABLE TO AMYLOID ACCUMULATION AND COMPOSITION FOR IMAGE DIAGNOSIS CONTAINING THE SAME

Document Type and Number:

WIPO Patent Application WO/2001/070667

Kind Code:

A1

Abstract:

A compound represented by the formula (I) or a salt or solvate thereof; and a composition and a kit both containing any of these. In said formula X represents CH, sulfur, or nitrogen; Y represents CH, sulfur, or nitrogen or is absent; (a) means a single bond or a double bond; A and B each independently represents a benzene ring or a six-membered heterocycle containing one or two atoms of nitrogen, oxygen, or sulfur; and R?1¿ and R?2¿ represent one to seven substituents of ring A and ring B, respectively.

Inventors:

KUDO YUKITSUKA (JP)
SUZUKI MASAKO (JP)
SUEMOTO TAKAHIRO (JP)
SHIMAZU HIROSHI (JP)

Application Number:

PCT/JP2001/002204

Publication Date:

September 27, 2001

Filing Date:

March 21, 2001

Export Citation:

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Assignee:

BF RES INST INC (JP)
KUDO YUKITSUKA (JP)
SUZUKI MASAKO (JP)
SUEMOTO TAKAHIRO (JP)
SHIMAZU HIROSHI (JP)

International Classes:

A61K51/04; C07C211/50; C07C245/08; C07C251/22; C07C251/24; C07C309/46; C07C309/47; C07C309/88; C07C323/35; C07C323/38; C07C331/28; (IPC1-7): C07C211/53; A61K51/04; C07C245/08; C07C251/22; C07C251/24; C07C275/40; C07C309/46; C07C309/88; C07C321/28; C07C331/28; C07D213/38; C07D213/76; C07D215/12; C07D221/10; C07D239/26

Domestic Patent References:

WO1998040071A1	1998-09-17
WO1999024394A2	1999-05-20

Foreign References:

EP0287909A1	1988-10-26
EP0290133A2	1988-11-09
EP0155551A1	1985-09-25

Other References:

ATTINA MARINA ET AL.: "Labeled aryl fluorides from the nucleophilic displacement of activated nitro groups by fluoride-18 ion", J. LABELLED COMPD. RADIOPHARM., vol. 20, no. 4, 1983, pages 501 - 514, XP002944123
See also references of EP 1266884A4

Attorney, Agent or Firm:

Aoyama, Tamotsu (IMP Building 3-7, Shiromi 1-chome, Chuo-k, Osaka-shi Osaka, JP)

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