Title:
IMIDAZO[1,2-A]PYRIDINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
Document Type and Number:
WIPO Patent Application WO/2013/081094
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a compound that can act on mGluR5 selectively to inhibit the signaling of mGluR5. The present invention provides an imidazo[1,2-a]pyridine derivative typified by the compound shown below or a pharmacologically acceptable acid addition salt thereof.
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Inventors:
OHYAMA TOMOFUMI (JP)
NUMAJIRI YOSHITAKA (JP)
NUMAJIRI YOSHITAKA (JP)
Application Number:
PCT/JP2012/081040
Publication Date:
June 06, 2013
Filing Date:
November 30, 2012
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
C07D471/04; A61K31/444; A61P1/04; A61P13/10; A61P21/02; A61P25/04; A61P25/06; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00
Foreign References:
| JP2010524892A | 2010-07-22 | |||
| JP2006503038A | 2006-01-26 | |||
| JP2005514382A | 2005-05-19 | |||
| JP2007504229A | 2007-03-01 | |||
| JP2004510707A | 2004-04-08 |
Other References:
CARCACHE, D.: "Benzimidazoles as Potent and Orally Active mGlu5 Receptor Antagonists with an Improved PK Profile", ACS MEDICINAL CHEMISTRY LETTERS, vol. 2, no. 1, 2011, pages 58 - 62
HIROSHI NAGASE, SAISHIN SOYAKU KAGAKU, 1998, pages 243 - 248
HIROSHI NAGASE, SAISHIN SOYAKU KAGAKU, 1998, pages 243 - 248
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Claims:
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