IMMOBILIZATION OF MOLECULES ON SURFACES VIA POLYMER BRUSHES

Title:

IMMOBILIZATION OF MOLECULES ON SURFACES VIA POLYMER BRUSHES

Document Type and Number:

WIPO Patent Application WO2000043539

Kind Code:

A3

Abstract:

The invention relates to polyfunctional polymer monolayers (polymer brushes) comprising a multitude of polymer chains attached to a surface, with each polymer chain comprising a multitude of units carrying at least on functional group which allows the interaction of the polymer chain with a sample molecule.

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Inventors:

KLAPPROTH HOLGER (DE)
PRUCKER OSWALD (DE)
RUEHE JUERGEN (DE)

Application Number:

PCT/EP2000/000554

Publication Date:

November 30, 2000

Filing Date:

January 25, 2000

Export Citation:

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Assignee:

BIOCHIP TECHNOLOGIES GMBH (DE)
KLAPPROTH HOLGER (DE)
PRUCKER OSWALD (DE)
RUEHE JUERGEN (DE)

International Classes:

B01J19/00; C08F2/00; C08F4/00; G01N33/53; C08F20/00; C12N15/09; C12Q1/68; G01N33/543; G01N33/545; G01N33/566; G01N37/00; C40B40/06; (IPC1-7): C12Q1/68; B01J19/00; G01N33/543

Domestic Patent References:

WO1997041425A1	1997-11-06
WO1990005303A1	1990-05-17
WO1997004129A1	1997-02-06

Other References:

SÖNKSEN C.P. ET AL.,: "Combining Maldi mass spectrometry and biomolecular interaction analysis using a biomolecular interaction analysis instrument", ANAL. CHEM., vol. 70, - 1 July 1998 (1998-07-01), pages 2731 - 2736, XP002111582
THIEL A J ET AL: "IN SITU SURFACE PLASMON RESONANCE IMAGING DETECTION OF DNA HYBRIDIZATION TO OLIGONUCLEOTIDE ARRAYS ON GOLD SURFACES", ANALYTICAL CHEMISTRY, vol. 69, no. 24, 15 December 1997 (1997-12-15), pages 4948 - 4956, XP000733394, ISSN: 0003-2700
RIBBE A. ET AL.,: "Imaging of polymer monolayers attached to silica surfaces by element specific transmission electron microscopy", POLYMER, vol. 37, no. 7, - 1996, pages 1087 - 1093, XP002111583

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