Title:
A IMMOUNLOGICAL EPITOPE OF THE HIV STRAIN TYPE O AND THE USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2004/011490
Kind Code:
A1
Abstract:
The present invention relates to a new immounlogical epitope of the HIV strain Type O and the uses thereof. The present invention provides a new immounlogical epitope of the HIV strain Type O. The N-end of the epitope is asparagine, its C-end is two adjacent residues of glutamic acid. The N-end of the epitope being consist of two amino acid residues usually links with the leucine residue. The C-end of the epitope usually ligates to the tryptophan residue. The amino acid sequence of the immounlogical epitope is LDEW. Based on the sequence, the N-end of it usually ligates to the glutamic acid residue. The C-end of it usually links with the alanine residue, So the amino acid sequence of the immounlogical epitope is ELDEWA. The epitope can be used as target for the identification and diagnosis of the HIV-1 Type O, also as target for drugs.
More Like This:
Inventors:
CHEN YINGHUA (CN)
DONG XIAONAN (CN)
XIAO YI (CN)
DONG XIAONAN (CN)
XIAO YI (CN)
Application Number:
PCT/CN2002/000552
Publication Date:
February 05, 2004
Filing Date:
August 09, 2002
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
BEIJING QINGDA YINGHUA BIO TEC (CN)
CHEN YINGHUA (CN)
DONG XIAONAN (CN)
XIAO YI (CN)
BEIJING QINGDA YINGHUA BIO TEC (CN)
CHEN YINGHUA (CN)
DONG XIAONAN (CN)
XIAO YI (CN)
International Classes:
A61K39/21; C07K14/155; C07K14/16; C07K16/08; C07K16/10; C12N5/12; C12N7/00; C12P21/08; C12Q1/00; G01N33/569; (IPC1-7): C07K14/155; C07K16/08; C12N5/12
Domestic Patent References:
| WO1991013909A1 | 1991-09-19 | |||
| WO1994029339A1 | 1994-12-22 |
Foreign References:
| EP0492560A2 | 1992-07-01 |
Attorney, Agent or Firm:
JEEKAI & PARTNERS (Jinyu Tower A129 West Xuan Wu Men Street, Beijing 1, CN)
Download PDF: