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Title:
IMMUNE BALANCE ADJUSTMENT AGENT
Document Type and Number:
WIPO Patent Application WO/2015/156339
Kind Code:
A1
Abstract:
Provided is a novel immune balance adjustment agent for adjusting the immune balance of an organism. This immune balance adjustment agent is one which: contains a euglena-derived substance; and adjusts the Th1/Th2/Th17 immune balance, which is the balance of immune responses derived from Th1, Th2 and Th17 in the organism. The immune balance adjustment agent is used to improve physical constitutions in which the Th1/Th2/Th17 immune balance leans toward Th2, and in the prevention or treatment of diseases to which a lean toward Th2 in the Th1/Th2/Th17 immune balance contributes, by adjusting the Th1/Th2/Th17 immune balance in a manner such that the immune response derived from Th1 is adjusted in a relatively superior direction relative to the immune responses derived from Th2 or Th17. This agent is to be administered prior to the period during which the onset of a disease to which a lean toward Th2 in the Th1/Th2/Th17 immune balance contributes is predicted.

Inventors:
NAKASHIMA AYAKA (JP)
ASAYAMA YUTA (JP)
YOSHIDA ERIKO (JP)
IWATA OSAMU (JP)
SUZUKI KENGO (JP)
Application Number:
PCT/JP2015/061043
Publication Date:
October 15, 2015
Filing Date:
April 08, 2015
Export Citation:
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Assignee:
EUGLENA CO LTD (JP)
International Classes:
A23L1/30; A61K36/05; A61K31/716; A61P1/04; A61P29/00; A61P31/00; A61P31/16; A61P37/02; A61P37/08; A61P43/00; C12N1/10
Domestic Patent References:
WO2013126669A12013-08-29
Foreign References:
JPH0454125A1992-02-21
JPH0665084A1994-03-08
JPH03505101A1991-11-07
JP2013075869A2013-04-25
JP2011184371A2011-09-22
JP2009062337A2009-03-26
JP2014118374A2014-06-30
JPH03227939A1991-10-08
Other References:
SUGIYAMA, A. ET AL.: "Hepatoprotective effects of paramylon, a beta-1, 3-D-glucan isolated from Euglena gracilis Z, on acute liver injury induced by carbon tetrachloride in rats", THE JOURNAL OF VETERINARY MEDICAL SCIENCE, vol. 71, no. 7, 2009, pages 885 - 890, XP055230361
AYAKA NAKAJIMA: "Midorimushi (Euglena", ANTI- AGING MEDICINE - JAPANESE SOCIETY OF ANTI-AGING MEDICINE ZASSHI, vol. 10, no. 5, 10 October 2014 (2014-10-10), pages 745 - 751
AYAKA NAKAJIMA ET AL.: "Euglena gracilis Z Oyobi sono To Chozo Busshitsu no Influenza Shojo no Kanwa Koka ni Kansuru Kensho", DAI 62 KAI THE JAPANESE SOCIETY OF VIROLOGY GAKUJUTSU SHUKAI PROGRAM · SHOROKU-SHU, 31 October 2014 (2014-10-31), pages 375
JESENAK, M. ET AL.: "beta-Glucans in the treatment and prevention of allergic diseases", ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol. 42, no. 2, 17 December 2012 (2012-12-17), pages 149 - 156
Attorney, Agent or Firm:
AKIYAMA, Atsushi et al. (JP)
Akiyama 敦 (JP)
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