Title:
IMMUNOGLOBULIN BINDING PROTEIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/055988
Kind Code:
A1
Abstract:
Provided are an isolated polypeptide consisting of a mutant B domain of Protein A, an unnatural immunoglobulin binding protein containing the mutant B domain, a conjugate containing the mutant B domain or the unnatural immunoglobulin binding protein, and the related uses.
Inventors:
WANG CHAO (CN)
LIAO HUAYUAN (CN)
BAI QI (CN)
GAO WEI (CN)
DING YAN (CN)
JIANG PEIJUAN (CN)
LIAO HUAYUAN (CN)
BAI QI (CN)
GAO WEI (CN)
DING YAN (CN)
JIANG PEIJUAN (CN)
Application Number:
PCT/CN2023/118531
Publication Date:
March 21, 2024
Filing Date:
September 13, 2023
Export Citation:
Assignee:
BIOTHEUS INC (CN)
International Classes:
C07K14/31; B01D15/38; C07K1/22; C07K16/06; C12N1/15; C12N15/11
Foreign References:
| CN107001432A | 2017-08-01 | |||
| CN109219613A | 2019-01-15 | |||
| CN102516371A | 2012-06-27 | |||
| CN105377880A | 2016-03-02 | |||
| CN107922483A | 2018-04-17 | |||
| CN103037885A | 2013-04-10 | |||
| CN110799521A | 2020-02-14 | |||
| CN112639099A | 2021-04-09 | |||
| US20150152195A1 | 2015-06-04 |
Other References:
LIN ZIYU, DING YINGYING; ZHOU PENG: "Construction And Evolutional Selection of A Combinatorial Phage Library Displaying Randomly-Rearranged Mutant Binding Domains of SPA", ACTA UNIVERSITATIS MEDICINALIS ANHUI, vol. 50, no. 9, 30 September 2015 (2015-09-30), pages 1262 - 1267, XP093146253, ISSN: 1000-1492, DOI: 10.19405/j.cnki.issn1000-1492.2015.09.013
MEININGER, D. P. ET AL.: "Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment", BIOCHEMISTRY, vol. 39, no. 1, 11 January 2000 (2000-01-11), pages 26 - 36, XP001008600, DOI: 10.1021/bi9920174
MEININGER, D. P. ET AL.: "Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment", BIOCHEMISTRY, vol. 39, no. 1, 11 January 2000 (2000-01-11), pages 26 - 36, XP001008600, DOI: 10.1021/bi9920174
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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