Title:
IMPLANT MATERIAL COMPRISING POLYETHERETHERKETON (PEEK) SURFACE-MODIFIED WITH THIOLATED HEPARIN AND BONE MORPHOGENETIC PROTEIN-2 (BMP-2), AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2023/085540
Kind Code:
A1
Abstract:
The present invention relates to an implant material comprising polyetheretherketone (PEEK) surface-modified with thiolated heparin and bone morphogenetic protein-2 (BMP-2) and a method for manufacturing same. The implant material comprising surface-modified polyetheretherketone (PEEK) according to the present invention is inexpensive, easy to handle, can be applied to implants having a complex shape, efficiently loads BMP-2 compared to unmodified PEEK, and can be released for a longer time to improve the osseointegration and osteogenic activity of pre-osteoblast cells, and thereby can be helpfully used as a dental or orthopedic implant.
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Inventors:
TAE GI YOONG (KR)
KIM YOUNG HA (KR)
GOH MEEI CHYN (KR)
KIM YOUNG HA (KR)
GOH MEEI CHYN (KR)
Application Number:
PCT/KR2022/007023
Publication Date:
May 19, 2023
Filing Date:
May 17, 2022
Export Citation:
Assignee:
GWANGJU INST SCIENCE & TECH (KR)
International Classes:
A61L27/54; A61C8/00; A61C8/02; A61F2/28; A61F2/30; A61L27/18; A61L27/28
Foreign References:
| KR101920284B1 | 2018-11-21 | |||
| KR101768160B1 | 2017-08-16 | |||
| JP2008500104A | 2008-01-10 | |||
| KR102264231B1 | 2021-06-11 | |||
| KR20160100057A | 2016-08-23 |
Attorney, Agent or Firm:
JIDAM IP LAW FIRM (KR)
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