Title:
IMPLANT MATERIAL AND IMPLANT SUITABLE FOR BONE DEFECT AND SPINAL FUSION TRANSPLANTATION AND PREPARATION METHOD FOR IMPLANT MATERIAL
Document Type and Number:
WIPO Patent Application WO/2022/033260
Kind Code:
A1
Abstract:
An implant material and an implant suitable for bone defect and spinal fusion transplantation and a preparation method. The implant material is used for filling an inner cavity of a titanium metal cage support (10) or a bone defect part, and is composed of an upper layer (21), a lower layer (22), and a middle layer located between the upper layer (21) and the lower layer (22). The middle layer is composed of an annular wrapping area (23) located on the periphery and a central area (24) located in the annular wrapping area. The central area (24) is filled with a first filling material, and the first filling material is a gel material having an osteogenesis promoting effect; the annular wrapping area (23) is filled with a second filling material, and the second filling material is a gel material having an epigenetic regulation effect; the upper layer (21) and the lower layer (22) are filled with a third filling material, and the third filling material is a gel material having the effects of regulating immune inflammation and stress reaction. The implant can adapt to microenvironments of different areas of a damaged part and orderly adjust a repair process, and is suitable for bone defect and spinal fusion transplantation.
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Inventors:
ZOU XUENONG (CN)
YI HUALIN (CN)
CHEN JUN (CN)
WANG GANG (CN)
CHEN YAN (CN)
HU HAO (CN)
YI HUALIN (CN)
CHEN JUN (CN)
WANG GANG (CN)
CHEN YAN (CN)
HU HAO (CN)
Application Number:
PCT/CN2021/105956
Publication Date:
February 17, 2022
Filing Date:
July 13, 2021
Export Citation:
Assignee:
THE FIRST AFFILIATED HOSPITAL SUN YAT SEN UNIV (CN)
International Classes:
A61L27/10; A61F2/28; A61F2/44; A61L27/20; A61L27/22; A61L27/50; A61L27/52; A61L27/54
Domestic Patent References:
| WO2014110353A1 | 2014-07-17 |
Foreign References:
| CN111921009A | 2020-11-13 | |||
| CN212756629U | 2021-03-23 | |||
| CN204542472U | 2015-08-12 | |||
| CN102440852A | 2012-05-09 | |||
| CN111450324A | 2020-07-28 | |||
| CN104353121A | 2015-02-18 | |||
| CN101043909A | 2007-09-26 |
Attorney, Agent or Firm:
GUANGZHOU SINO PATENT & TRADEMARK AGENT CO., LTD. (CN)
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