Title:
IMPROVED CAPPING MODULES FOR DESIGNED ANKYRIN REPEAT PROTEINS
Document Type and Number:
WIPO Patent Application WO/2012/069655
Kind Code:
A3
Abstract:
Improved N-terminal capping modules for designed ankyrin repeat proteins (DARPins) conferringimproved thermal stabilityto the DARPins are described, as well as nucleic acids encoding such proteins, pharmaceutical compositions comprising such proteins and the use of such proteins in the treatment of diseases.
Inventors:
BINZ HANS KASPAR (CH)
Application Number:
PCT/EP2011/071084
Publication Date:
July 19, 2012
Filing Date:
November 25, 2011
Export Citation:
Assignee:
MOLECULAR PARTNERS AG (CH)
BINZ HANS KASPAR (CH)
BINZ HANS KASPAR (CH)
International Classes:
C07K14/47
Domestic Patent References:
| WO2010060748A1 | 2010-06-03 | |||
| WO2009115919A2 | 2009-09-24 |
Other References:
See also references of EP 2643348A2
Attorney, Agent or Firm:
BECKER, Konrad (Postfach 318, Basel, CH)
Download PDF:
Previous Patent: DESIGNED REPEAT PROTEINS BINDING TO SERUM ALBUMIN
Next Patent: SELF-PROPELLED GOLF VEHICLE
Next Patent: SELF-PROPELLED GOLF VEHICLE