Title:
IMPROVED GUIDED EDITING SYSTEM
Document Type and Number:
WIPO Patent Application WO/2023/030534
Kind Code:
A1
Abstract:
Provided are an improved guided editing system, and a method for performing gene editing by the system.
More Like This:
Inventors:
GAO CAIXIA (CN)
ZONG YUAN (CN)
ZONG YUAN (CN)
Application Number:
PCT/CN2022/117258
Publication Date:
March 09, 2023
Filing Date:
September 06, 2022
Export Citation:
Assignee:
SUZHOU QI BIODESIGN BIOTECHNOLOGY COMPANY LTD (CN)
International Classes:
C12N15/82; A01H5/00; C12N15/62
Domestic Patent References:
| WO2021082830A1 | 2021-05-06 | |||
| WO2021165508A1 | 2021-08-26 | |||
| WO2021080922A1 | 2021-04-29 | |||
| WO2021092204A1 | 2021-05-14 | |||
| WO2018149418A1 | 2018-08-23 |
Other References:
MARTÍN-ALONSO SAMARA; FRUTOS-BELTRÁN ESTRELLA; MENÉNDEZ-ARIAS LUIS: "Reverse Transcriptase: From Transcriptomics to Genome Editing", TRENDS IN BIOTECHNOLOGY, vol. 39, no. 2, 8 July 2020 (2020-07-08), GB , pages 194 - 210, XP086446241, ISSN: 0167-7799, DOI: 10.1016/j.tibtech.2020.06.008
AREZI BAHRAM , HOGREFE HOLLY: "Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer.", NUCLEIC ACIDS RESEARCH, vol. 37, no. 2, 1 February 2009 (2009-02-01), GB , pages 473 - 481, XP002556110, ISSN: 1362-4962, DOI: 10.1093/nar/gkn952
YASUKAWA KIYOSHI, YANAGIHARA ITARU, FUJIWARA SHINSUKE: "Alteration of enzymes and their application to nucleic acid amplification (Review)", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, vol. 46, no. 5, 1 November 2020 (2020-11-01), GR , pages 1633 - 1643, XP093042055, ISSN: 1107-3756, DOI: 10.3892/ijmm.2020.4726
SAMBROOK, J.FRITSCH, E.F.MANIATIS, T.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
GAO ET AL., JIPB, vol. 56, April 2014 (2014-04-01), pages 343 - 349
JAMES W. NELSON ET AL.: "Engineered pegRNAs improve prime editing efficiency", NATURE BIOTECHNOLOGY, vol. 40, 2022, pages 402 - 410, XP093043230, DOI: 10.1038/s41587-021-01039-7
CODON USAGE DATABASE, Retrieved from the Internet
NAKAMURA, Y ET AL.: "Codon usage tabulated from the international DNA sequence databases: status for the year 2000", NUCL. ACIDS RES., vol. 28, 2000, pages 292, XP002941557, DOI: 10.1093/nar/28.1.292
AREZI BAHRAM , HOGREFE HOLLY: "Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer.", NUCLEIC ACIDS RESEARCH, vol. 37, no. 2, 1 February 2009 (2009-02-01), GB , pages 473 - 481, XP002556110, ISSN: 1362-4962, DOI: 10.1093/nar/gkn952
YASUKAWA KIYOSHI, YANAGIHARA ITARU, FUJIWARA SHINSUKE: "Alteration of enzymes and their application to nucleic acid amplification (Review)", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, vol. 46, no. 5, 1 November 2020 (2020-11-01), GR , pages 1633 - 1643, XP093042055, ISSN: 1107-3756, DOI: 10.3892/ijmm.2020.4726
SAMBROOK, J.FRITSCH, E.F.MANIATIS, T.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
GAO ET AL., JIPB, vol. 56, April 2014 (2014-04-01), pages 343 - 349
JAMES W. NELSON ET AL.: "Engineered pegRNAs improve prime editing efficiency", NATURE BIOTECHNOLOGY, vol. 40, 2022, pages 402 - 410, XP093043230, DOI: 10.1038/s41587-021-01039-7
CODON USAGE DATABASE, Retrieved from the Internet
NAKAMURA, Y ET AL.: "Codon usage tabulated from the international DNA sequence databases: status for the year 2000", NUCL. ACIDS RES., vol. 28, 2000, pages 292, XP002941557, DOI: 10.1093/nar/28.1.292
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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