Title:
IMPROVED IMMUNOTHERAPEUTIC METHOD OF PREVENTING OR TREATING VIRAL RESPIRATORY TRACT DISEASE
Document Type and Number:
WIPO Patent Application WO1992001473
Kind Code:
A1
Abstract:
An improved immunotherapeutic method of preventing or treating viral respiratory tract disease is described. The method comprises administering into the lower respiratory tract of a susceptible host a small particle (< 2 mu m) aerosol of a mixture of specific monoclonal antibodies directed against the various protective antigenic sites present on a major protective viral surface antigen(s).
Inventors:
CHANOCK ROBERT MERRITT (US)
PRINCE GREGORY ANTONE (US)
COELINGH KATHLEEN LOUISE (US)
MURPHY BRIAN ROBERT (US)
HEMMING VAL (US)
BEELER JUDY ALLYSON (US)
PRINCE GREGORY ANTONE (US)
COELINGH KATHLEEN LOUISE (US)
MURPHY BRIAN ROBERT (US)
HEMMING VAL (US)
BEELER JUDY ALLYSON (US)
Application Number:
PCT/US1991/005002
Publication Date:
February 06, 1992
Filing Date:
July 19, 1991
Export Citation:
Assignee:
US COMMERCE (US)
International Classes:
A61K39/395; A61P31/12; C07K16/10; A61K38/00; (IPC1-7): A61K39/395
Foreign References:
| US4965069A | 1990-10-23 | |||
| US4933169A | 1990-06-12 |
Other References:
Journal of Virology, Volume 63, Number 1, issued January 1989, COELINGH et al., "Antigenic and Functional organization of Human Para influensa Virus Type 3 Fusion Glycoprotein", pages 375-382, see the entire document.
Journal of Virology, Volume 62, Number 11, issued November 1988, ANDERSON et al., "Neutralization of Respiratory Syncytial Virus by Individual and Mixtures of F and G protein monoclonal antibodies", pages 4232-4238, see the entire document.
Journal of Virology, Volume 62, Number 11, issued November 1988, ANDERSON et al., "Neutralization of Respiratory Syncytial Virus by Individual and Mixtures of F and G protein monoclonal antibodies", pages 4232-4238, see the entire document.
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