Title:
IMPROVED INHIBITORY DNA COMPOSITIONS AND USE THEREOF, IN PARTICULAR INTEGRATED WITH METABOLIC TREATMENT TO ENHANCE INHIBITORY EFFECTS
Document Type and Number:
WIPO Patent Application WO/2023/012845
Kind Code:
A3
Abstract:
The present invention concerns compositions suitable for inhibiting a target species or a target cancer cell of a species, methods and uses of the compositions, wherein the compositions comprise DNA sequences secreted by the cells of a species identical or phylogenetically similar to the target species or by a cancer cell affected by the same cancer as the target cancer cell of a species. The compositions according to the present invention can be advantageously used in any field where the inhibition of a species or of a cancer cell is beneficial, for example in human and/or veterinary medicine or in agriculture for the control of pest or diseases.
Inventors:
MAZZOLENI STEFANO (IT)
Application Number:
PCT/IT2022/050221
Publication Date:
March 16, 2023
Filing Date:
August 04, 2022
Export Citation:
Assignee:
NO SELF S R L (IT)
International Classes:
A61P35/00; A01N63/60; A61K39/00; C12N5/04; C12N15/11
Domestic Patent References:
| WO2016198950A2 | 2016-12-15 | |||
| WO2014020624A2 | 2014-02-06 | |||
| WO2020167240A1 | 2020-08-20 |
Foreign References:
| US20200368336A1 | 2020-11-26 |
Other References:
VERESOGLOU S.D. ET AL: "Letters Self-DNA: a blessing in disguise?", NEW PHYTOLOGIST, vol. 207, 19 April 2015 (2015-04-19), pages 488 - 490, XP055931241
M. C. HAWES ET AL: "Extracellular DNA: A Bridge to Cancer", CANCER RESEARCH, vol. 75, no. 20, 15 October 2015 (2015-10-15), US, pages 4260 - 4264, XP055379708, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-15-1546
ANUNOBI REGINALD ET AL: "Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy", JOURNAL OF SURGICAL RESEARCH, ACADEMIC PRESS INC., SAN DIEGO, CA, US, vol. 226, 28 March 2018 (2018-03-28), pages 181 - 191, XP085379070, ISSN: 0022-4804, DOI: 10.1016/J.JSS.2018.02.042
M. C. HAWES ET AL: "Extracellular DNA: A Bridge to Cancer", CANCER RESEARCH, vol. 75, no. 20, 15 October 2015 (2015-10-15), US, pages 4260 - 4264, XP055379708, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-15-1546
ANUNOBI REGINALD ET AL: "Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy", JOURNAL OF SURGICAL RESEARCH, ACADEMIC PRESS INC., SAN DIEGO, CA, US, vol. 226, 28 March 2018 (2018-03-28), pages 181 - 191, XP085379070, ISSN: 0022-4804, DOI: 10.1016/J.JSS.2018.02.042
Attorney, Agent or Firm:
GITTO, Serena et al. (IT)
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