Title:
IMPROVED ISOLATION OF PHENYL ESTER SALTS FROM MIXTURES COMPRISING SULFOLANE
Document Type and Number:
WIPO Patent Application WO2001094303
Kind Code:
A3
Abstract:
The invention relates to a process for isolating a phenyl ester salt from a mixture comprising sulfolane (tetrahydrothiophene-1,1-dioxide). The invention includes adjusting the temperature of a mixture comprising a phenyl ester salt and sulfolane to a temperature of about 100-150 DEG C. This step leads to the formation of a mixture comprising a solid phenyl ester salt and sulfolane. Next, the solid phenyl ester salt is separated, while maintaining the temperature of the mixture at about 100-150 DEG C. The invention also relates to a process that includes adding a sufficient amount of a solvent to a mixture comprising a phenyl ester salt and sulfolane to decrease the viscosity or the density of the mixture. The solvent added has a density less than about 1.20 g/cm3 at 100 DEG C or a viscosity of less than about 2.56 centipoise at 100 DEG C. The embodiments of the invention may be used alone or in combination. This invention may be used for the isolation of a variety of phenyl ester salts, including but not limited to sodium 4-sulfophenyl-6-[(1-oxynonyl)amino] hexanoate, sodium 4-(nonanoyloxy) benzenesulfonate, and sodium benzoyloxybenzenesulphonate.
Inventors:
FONTENOT KEVIN J
ATTRIDE DAVID C
TERHUNE KEITH B
ATTRIDE DAVID C
TERHUNE KEITH B
Application Number:
PCT/US2001/017969
Publication Date:
August 08, 2002
Filing Date:
June 04, 2001
Export Citation:
Assignee:
EASTMAN CHEM CO (US)
International Classes:
C07C303/44; C07C309/42; (IPC1-7): C07C303/44; C07C309/42
Foreign References:
| US5650527A | 1997-07-22 |
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