Title:
IMPROVED METHOD FOR FREEZING VIABLE CELLS
Document Type and Number:
WIPO Patent Application WO2003020874
Kind Code:
A3
Abstract:
A method and a device (50) for improved freezing of biological samples containing living cells is disclosed. Directional cooling coupled with agitation, preferably rotation, of the vessel (12) containing the biological sample (14) allows for the freezing of large volume samples at much greater rates than before. Whether a sample is large or not, the greater thermal homogeneity during the freezing process as well as the resulting crystal morphology yield a frozen sample which is exceptionally suited for lyophilization.
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Inventors:
NATAN YEHUDIT (IL)
URI MEIR (IL)
URI MEIR (IL)
Application Number:
PCT/IL2002/000738
Publication Date:
September 25, 2003
Filing Date:
September 05, 2002
Export Citation:
Assignee:
IMT INTERFACE MULTIGRAD TECH LTD (IL)
NATAN YEHUDIT (IL)
URI MEIR (IL)
NATAN YEHUDIT (IL)
URI MEIR (IL)
International Classes:
A01N1/02; B01L7/00; F25D3/02; F26B5/06; F25C1/20; F25D3/11; G01N1/42; (IPC1-7): G01N1/42
Foreign References:
| US5873254A | 1999-02-23 | |||
| US5059518A | 1991-10-22 | |||
| US6073540A | 2000-06-13 | |||
| US5071598A | 1991-12-10 | |||
| US5364756A | 1994-11-15 | |||
| US4874690A | 1989-10-17 | |||
| JP2000189155A | 2000-07-11 |
Other References:
DATABASE WPI Derwent World Patents Index; AN 1994-223708, XP002961154
See also references of EP 1428008A4
See also references of EP 1428008A4
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