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Title:
IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE
Document Type and Number:
WIPO Patent Application WO/2019/044947
Kind Code:
A1
Abstract:
Provided are a crystal of the compound represented by formula (1), a method for producing the crystal, and a method for producing an antibody-drug conjugate using said crystal.

Inventors:
YAMAGUCHI Tatsuya (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
KOUKO Takashi (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
NOGUCHI Shigeru (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
YAMANE Yohei (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
KONDO Fumikatsu (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
AOKI Takahiro (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
TAKEDA Tadahiro (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
SAKANISHI Kohei (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
SATO Hitoshi (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
UEDA Tsuyoshi (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
MATUURA Shinji (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
KURAHASHI Kei (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
KITAGAWA Yutaka (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
NAKAMURA Tatsuya (LIMITED 3-5-1, Nihonbashi Honcho, Chuo-k, Tokyo 26, 〒1038426, JP)
Application Number:
JP2018/032056
Publication Date:
March 07, 2019
Filing Date:
August 30, 2018
Export Citation:
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Assignee:
DAIICHI SANKYO COMPANY, LIMITED (3-5-1, Nihonbashi Honcho Chuo-k, Tokyo 26, 〒1038426, JP)
International Classes:
C07K5/10; A61K39/395; A61K47/65; A61P35/00; C07C237/08
Domestic Patent References:
WO2014057687A12014-04-17
WO2015115091A12015-08-06
WO2015098099A12015-07-02
WO2015155998A12015-10-15
Foreign References:
JPH0680891A1994-03-22
JP2005343837A2005-12-15
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (LIMITED 1-2-58, Hiromachi, Shinagawa-k, Tokyo 05, 〒1400005, JP)
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