Title:
IMPROVED PROCESS FOR THE PREPARATION OF 0-DESMETHYL-VENLAFAXINE
Document Type and Number:
WIPO Patent Application WO/2009/084038
Kind Code:
A3
Abstract:
The present invention relates to an industrially advantageous process for the preparation of O- desmethyl-venlafaxine, a venlafaxine metabolite, and pharmaceutically acceptable salts thereof by demethylating venlafaxine or salts using an alkali or alkaline earth metal salts of mercapto acids and their derivatives, mercapto alcohols, heterocyclic mercaptans, xanthates and thioacids and the like or mixture thereof in presence of an organic solvent.
Inventors:
SRINIVASAN CHIDAMBARAM VENKATESWARAN (IN)
AGGARWAL ASHVIN KUMAR (IN)
SARIN GURDEEP SINGH (IN)
WADHWA LALIT (IN)
AGGARWAL ASHVIN KUMAR (IN)
SARIN GURDEEP SINGH (IN)
WADHWA LALIT (IN)
Application Number:
PCT/IN2008/000856
Publication Date:
January 27, 2011
Filing Date:
December 23, 2008
Export Citation:
Assignee:
IND SWIFT LAB LTD (IN)
SRINIVASAN CHIDAMBARAM VENKATESWARAN (IN)
AGGARWAL ASHVIN KUMAR (IN)
SARIN GURDEEP SINGH (IN)
WADHWA LALIT (IN)
SRINIVASAN CHIDAMBARAM VENKATESWARAN (IN)
AGGARWAL ASHVIN KUMAR (IN)
SARIN GURDEEP SINGH (IN)
WADHWA LALIT (IN)
International Classes:
C07C209/68; C07C213/00; C07C215/52
Domestic Patent References:
| WO2003048104A1 | 2003-06-12 | |||
| WO2007120923A1 | 2007-10-25 |
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