Title:
AN IMPROVED PROCESS FOR THE PREPARATION OF FIDAXOMICIN
Document Type and Number:
WIPO Patent Application WO/2014/174528
Kind Code:
A3
Abstract:
The present invention provides an improved process for the preparation of fidaxomicin by culturing Actinoplanes deccanensis in the culture medium of the invention wherein the fidaxomicin is produced in a yield of greater than 500mg/L broth. The present invention also provides a whole broth extraction process for the isolation of fidaxomicin from the fermentation broth. The present invention also provides fidaxomicin having purity of greater than 97% area by HPLC.
Inventors:
VAID ANKUR SUDHIR (IN)
PATEL MITESH JAGDISHKUMAR (IN)
MEHTA DHIMANT PUNJALAL (IN)
DHIMAN ANAND MAHADEV (IN)
PATEL JAYESH CHANDUBHAI (IN)
SHARMA TRAUNKANT PARSHURAM (IN)
PATEL MITESH JAGDISHKUMAR (IN)
MEHTA DHIMANT PUNJALAL (IN)
DHIMAN ANAND MAHADEV (IN)
PATEL JAYESH CHANDUBHAI (IN)
SHARMA TRAUNKANT PARSHURAM (IN)
Application Number:
PCT/IN2014/000251
Publication Date:
December 24, 2014
Filing Date:
April 21, 2014
Export Citation:
Assignee:
CONCORD BIOTECH LTD (IN)
International Classes:
C12N1/00; C12P1/00
Foreign References:
| US7507564B2 | 2009-03-24 | |||
| US4918174A | 1990-04-17 | |||
| US3978211A | 1976-08-31 | |||
| US4169887A | 1979-10-02 |
Attorney, Agent or Firm:
ACHARYA, Rajeshkumar H. et al. (19 Swastik Society,Navrangpura, Ahmedabad 9, IN)
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