Title:
AN IMPROVED PROCESS FOR THE PREPARATION OF INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET
Document Type and Number:
WIPO Patent Application WO/2010/128388
Kind Code:
A3
Abstract:
The present invention provides an improved process for the preparation of 3-[3-(trifluoromethyl)phenyl]-2-propenal (IIIa), (formula IIIa) and 3-[3-(trifluoromethyl)phenyl]-2-propen-1-ol (IVb), (formula IVb) The compounds of Formula IIIa and IVb are key precursors in the preparation of Calcimimetic agent, Cinacalcet hydrochloride of Formula I.
Inventors:
DIVVELA VENKATA NAGA SRINIVASA RAO (IN)
GUNTUPALLY SRIKANTH (IN)
DEEKONDA SATHEESH (IN)
RACHA LENIN (IN)
RAY UTTAM KUMAR (IN)
ISLAM AMINUL (IN)
MEENAKSHISUNDERAM SIVAKUMARAN (IN)
GUNTUPALLY SRIKANTH (IN)
DEEKONDA SATHEESH (IN)
RACHA LENIN (IN)
RAY UTTAM KUMAR (IN)
ISLAM AMINUL (IN)
MEENAKSHISUNDERAM SIVAKUMARAN (IN)
Application Number:
PCT/IB2010/001057
Publication Date:
April 07, 2011
Filing Date:
May 10, 2010
Export Citation:
Assignee:
AUROBINDO PHARMA LTD (IN)
DIVVELA VENKATA NAGA SRINIVASA RAO (IN)
GUNTUPALLY SRIKANTH (IN)
DEEKONDA SATHEESH (IN)
RACHA LENIN (IN)
RAY UTTAM KUMAR (IN)
ISLAM AMINUL (IN)
MEENAKSHISUNDERAM SIVAKUMARAN (IN)
DIVVELA VENKATA NAGA SRINIVASA RAO (IN)
GUNTUPALLY SRIKANTH (IN)
DEEKONDA SATHEESH (IN)
RACHA LENIN (IN)
RAY UTTAM KUMAR (IN)
ISLAM AMINUL (IN)
MEENAKSHISUNDERAM SIVAKUMARAN (IN)
International Classes:
C07C33/30; C07C45/29; C07C47/24; C07C211/30
Foreign References:
| US5089513A | 1992-02-18 |
Other References:
OIDA S ET AL: "Synthesis and antifungal activities of R-102557 and related dioxane-triazole derivatives", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN, TOKYO, JP, vol. 48, no. 5, 1 May 2000 (2000-05-01), pages 694 - 707, XP002156630, ISSN: 0009-2363
J.IQBAL ET AL: "Cinacalcet hydrochloride", IDRUGS, vol. 6, no. 6, 2003, CURRENT DRUGS LTD, pages 587 - 592, XP002616108, ISSN: 1369-7056
J.IQBAL ET AL: "Cinacalcet hydrochloride", IDRUGS, vol. 6, no. 6, 2003, CURRENT DRUGS LTD, pages 587 - 592, XP002616108, ISSN: 1369-7056
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