Title:
IMPROVED STABILITY OF HYBRIDISATION INTERACTIONS IN DIPSTICK ASSAYS
Document Type and Number:
WIPO Patent Application WO2002004122
Kind Code:
B1
Abstract:
Use of probes with non complementary nucleotides in dipstick assays to test for the presence of a target nucleic acid in a sample solution is described. The probes have greater affinity for target nucleic acid and can be used in capture and/or detection of target nucleic acid. The sensitivity of target nucleic acid detection is thereby increased. Dipsticks and kits are also described.
Inventors:
LEE HELEN (GB)
DINEVA MAGDA ANASTASSOVA (GB)
DINEVA MAGDA ANASTASSOVA (GB)
Application Number:
PCT/GB2001/003047
Publication Date:
August 07, 2003
Filing Date:
July 06, 2001
Export Citation:
Assignee:
LEE HELEN (GB)
DINEVA MAGDA ANASTASSOVA (GB)
DINEVA MAGDA ANASTASSOVA (GB)
International Classes:
C12Q1/68; (IPC1-7): B01L3/00; C12Q1/68; G01F23/04; G01N33/558
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