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Title:
IMPROVED SYNTHESIS OF DISCODERMOLIDE AND VARIANTS THEREOF
Document Type and Number:
WIPO Patent Application WO2005035489
Kind Code:
A3
Abstract:
Processes for synthesizing a compound of Formula (I) are provided by reacting a compound of Formula (i) with a compound of Formula (xx).

Inventors:
SMITH AMOS B III (US)
FREEZE BRIAN SCOTT (US)
XIAN MING (US)
Application Number:
US2004033473W
Publication Date:
August 04, 2005
Filing Date:
October 12, 2004
Export Citation:
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Assignee:
UNIV PENNSYLVANIA (US)
SMITH AMOS B III (US)
FREEZE BRIAN SCOTT (US)
XIAN MING (US)
International Classes:
C07C31/34; C07C33/18; C07C33/42; C07D277/04; C07D309/00; C07D309/30; C07D315/00; C07F7/18; C07D; (IPC1-7): C07D236/02; C07C31/34; C07C33/18; C07C33/42; C07D277/04; C07D309/00; C07D309/30; C07D315/00
Other References:
GUNASEKERA S.P.: "Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: Preparation and biological activity", J. NAT. PROD., vol. 65, 2002, pages 1830 - 1837, XP002987289
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