Title:
IMPROVEMENTS IN AND RELATING TO DEVICES
Document Type and Number:
WIPO Patent Application WO/2016/012219
Kind Code:
A3
Abstract:
A device for sensing and/or detecting species or stimulus at a locus, preferably at a fluid or moist locus by means of fluid communication therewith, comprising a surface configured to contact the locus, wherein the surface comprises a polyurethane material which material comprises a polyurethane polymer network having a hydrophilic polymer immobilised therein wherein the hydrophilic polymer comprises immobilised therein a ligand or moiety for detecting or sensing species or stimulus and an indicator for indicating detection or sensing prior to contact with the locus and change in indication as a function of species or stimulus present at the locus wherein species or stimulus are selected from chemical and biological species or stimulus; the use thereof preferably for detecting and/or sensing or binding bacteria, or for detecting or sensing pH or for detection or scanning with use of a reader; and a Kit.
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Inventors:
HICKS JOHN KENNETH (GB)
RIMMER STEPHEN (GB)
HOSKINS RICHARD (GB)
MCCULLOCH DOROTHY (GB)
RIMMER STEPHEN (GB)
HOSKINS RICHARD (GB)
MCCULLOCH DOROTHY (GB)
Application Number:
PCT/EP2015/065227
Publication Date:
May 26, 2016
Filing Date:
July 03, 2015
Export Citation:
Assignee:
SMITH & NEPHEW (GB)
International Classes:
C08L75/04; A61L27/16; A61L27/22; A61L27/26; C08G18/10; G01N21/01; G01N21/77; G01N21/80
Foreign References:
| US20050187146A1 | 2005-08-25 | |||
| US6120904A | 2000-09-19 |
Other References:
THATIPARTI THIMMA REDDY ET AL: "Synthesis and characterization of semi-interpenetrating polymer networks based on polyurethane and N -isopropylacrylamide for wound dressing", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B: APPLIED BIOMATERIALS, vol. 88B, no. 1, 8 September 2008 (2008-09-08), pages 32 - 40, XP055217089, ISSN: 1552-4973, DOI: 10.1002/jbm.b.31185
CHUN-YEN CHEN ET AL: "A PNIPAM-based fluorescent nanothermometer with ratiometric readout", CHEMICAL COMMUNICATIONS, vol. 47, no. 3, 26 November 2010 (2010-11-26), pages 994 - 996, XP055217091, ISSN: 1359-7345, DOI: 10.1039/C0CC04450D
UCHIYAMA S ET AL: "FLUORESCENT MOLECULAR THERMOMETERS BASED ON POLYMERS SHOWING TEMPERATURE-INDUCED PHASE TRANSITIONS AND LABELED WITH POLARITY-RESPONSIVE BENZOFURAZANS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 75, no. 21, 4 October 2003 (2003-10-04), pages 5926 - 5935, XP001047338, ISSN: 0003-2700, DOI: 10.1021/AC0346914
CHUN-YEN CHEN ET AL: "A PNIPAM-based fluorescent nanothermometer with ratiometric readout", CHEMICAL COMMUNICATIONS, vol. 47, no. 3, 26 November 2010 (2010-11-26), pages 994 - 996, XP055217091, ISSN: 1359-7345, DOI: 10.1039/C0CC04450D
UCHIYAMA S ET AL: "FLUORESCENT MOLECULAR THERMOMETERS BASED ON POLYMERS SHOWING TEMPERATURE-INDUCED PHASE TRANSITIONS AND LABELED WITH POLARITY-RESPONSIVE BENZOFURAZANS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 75, no. 21, 4 October 2003 (2003-10-04), pages 5926 - 5935, XP001047338, ISSN: 0003-2700, DOI: 10.1021/AC0346914
Attorney, Agent or Firm:
CONNORS, Martin (York Science Park Heslington, York YO10 5DF, GB)
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