IMPROVEMENTS IN AND RELATING TO THE PRODUCTION AND CONTROL OF IONS

Title:

IMPROVEMENTS IN AND RELATING TO THE PRODUCTION AND CONTROL OF IONS

Document Type and Number:

WIPO Patent Application WO/2014/162299

Kind Code:

A3

Abstract:

An electrospray ionisation source for generating charged droplets of liquid entrained within a gas flow (109) within a vacuum chamber (107), comprising a liquid insertion capillary (105) for receiving a liquid external to the vacuum chamber and for outputting the received liquid at an output end of the liquid insertion capillary within the vacuum chamber thereby to insert the liquid into the vacuum chamber. A nebuliser part (102, 103) comprises one or more gas flow ducts (103) for receiving a gas (108) external to the vacuum chamber and for outputting the received gas at an output end (110) of the nebuliser part comprising output end(s) of the one or more said gas flow ducts within the vacuum chamber. This inserts a gas flow (109) into the vacuum chamber (107). A charger part (114, or 217) is provided for charging said droplets of said liquid output by said nebulizer part. The liquid insertion capillary is located within the output end of the nebuliser part so as to position the output end of the liquid insertion capillary within gas flows output by the nebuliser part, in use, to entrain charged droplets of the inserted liquid within flows of the inserted gas.

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Inventors:

RAPTAKIS EMMANUAL (GR)
PAPANASTASIOU DIMITRIS (GR)
KOUNADIS DIAMANTIS (GR)
LEKKAS ALEXANDER (GR)
ORFANOPOULOS IOANNIS (GR)

Application Number:

PCT/IB2014/060441

Publication Date:

March 05, 2015

Filing Date:

April 04, 2014

Export Citation:

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Assignee:

FASMATECH SCIENCE AND TECHNOLOGY SA (GR)

International Classes:

H01J49/16; H01J49/04

Foreign References:

US6068749A	2000-05-30
US5543618A	1996-08-06
GB2437844A	2007-11-07
EP1004878A1	2000-05-31

Other References:

JASON S PAGE ET AL: "Subambient Pressure Ionization with Nanoelectrospray Source and Interface for Improved Sensitivity in Mass Spectrometry", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 80, no. 5, 1 March 2008 (2008-03-01), pages 1800 - 1805, XP007910297, ISSN: 0003-2700, DOI: 10.1021/AC702354B

Attorney, Agent or Firm:

FEARNSIDE, Andrew Simon et al. (Halifax, Yorkshire HX1 2HY, GB)

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