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Title:
IN VITRO METHODS FOR DETECTING RENAL CANCER
Document Type and Number:
WIPO Patent Application WO2005003776
Kind Code:
A3
Abstract:
The present invention refers to an in vitro method for detecting the presence of renal cancer in an individual, for determining the stage, malignancy or severity of said carcinoma in the individual or for monitoring the effect of the therapy administered to an individual having said cancer; to the search, identification, development and assessment of the efficacy of compounds for therapy for said cancer in an attempt to develop new drugs; as well as to agents inducing Plexin-131 protein expression and/or activity, or to agents inhibiting the effects of Plexin-B1 protein expression and/or activity repression.

Inventors:
GOMEZ ROMAN JOSE JAVIER (ES)
SAENZ JIMENEZ MARIA PILAR (ES)
OCHOA GARAY JORGE (ES)
DEL AMO IRIBARREN JOKIN (ES)
SANZ IBAYONDO CRISTINA (ES)
JUNQUERA SANCHEZ-VALLEJO CORIN (ES)
SIMON BUELA LAUREANO (ES)
MARTINEZ MARTINEZ ANTONIO (ES)
ARGUEELLES SANCHEZ MARIA ELADI (ES)
VAL BERNAL JOSE FERNANDO (ES)
CUEVAS GONZALEZ JORGE (ES)
Application Number:
PCT/EP2004/007195
Publication Date:
April 21, 2005
Filing Date:
June 30, 2004
Export Citation:
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Assignee:
PROGENIKA BIOPHARMA SA (ES)
GOMEZ ROMAN JOSE JAVIER (ES)
SAENZ JIMENEZ MARIA PILAR (ES)
OCHOA GARAY JORGE (ES)
DEL AMO IRIBARREN JOKIN (ES)
SANZ IBAYONDO CRISTINA (ES)
JUNQUERA SANCHEZ-VALLEJO CORIN (ES)
SIMON BUELA LAUREANO (ES)
MARTINEZ MARTINEZ ANTONIO (ES)
ARGUEELLES SANCHEZ MARIA ELADI (ES)
VAL BERNAL JOSE FERNANDO (ES)
CUEVAS GONZALEZ JORGE (ES)
International Classes:
A61P35/00; C07K14/47; C07K14/705; C07K14/71; C12Q1/68; G01N33/574; (IPC1-7): G01N33/574; C12Q1/68; A61P35/00
Domestic Patent References:
WO2003031930A22003-04-17
WO2001014420A22001-03-01
WO2004050914A12004-06-17
Other References:
CIRCOSTA PAOLA ET AL: "CD100/Plexin-B1 interaction emphasizes the role of bone marrow microenvironment in B-CLL", BLOOD, vol. 98, no. 11 Part 1, 16 November 2001 (2001-11-16), & 43RD ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY, PART 1; ORLANDO, FLORIDA, USA; DECEMBER 07-11, 2001, pages 360a, XP009041247, ISSN: 0006-4971
GIESEG MICHAEL A ET AL: "Expression profiling of human renal carcinomas with functional taxonomic analysis.", BMC BIOINFORMATICS [ELECTRONIC RESOURCE]. 30 SEP 2002, vol. 3, no. 26, 30 September 2002 (2002-09-30), XP002309629, ISSN: 1471-2105
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