Title:
IN VIVO METHOD OF OBTAINING CELL COMPONENTS
Document Type and Number:
WIPO Patent Application WO1994015923
Kind Code:
A3
Abstract:
Cell contents are obtained from cells in vivo by transforming cells from a first state into a second state by subjecting them to stress conditions such that they are forced either to release cell contents into their environment or to synthesize cell contents in order to adapt themselves to the conditions of the second state; the procedure being repeated at least twice reverse stress. S,S-Alpha-amino-beta-hydroxyectoin of formula (I) is also claimed.
Inventors:
GALINSKI ERWIN A (DE)
TRUEPER HANS G (DE)
SAUER THOMAS (DE)
TRUEPER HANS G (DE)
SAUER THOMAS (DE)
Application Number:
PCT/EP1993/003687
Publication Date:
September 29, 1994
Filing Date:
December 24, 1993
Export Citation:
Assignee:
GALINSKI ERWIN A (DE)
TRUEPER HANS G (DE)
SAUER THOMAS (DE)
TRUEPER HANS G (DE)
SAUER THOMAS (DE)
International Classes:
A01N1/02; A61K8/49; A61K31/14; A61K31/505; A61K35/14; A61Q19/00; C07C257/10; C07D239/04; C07D239/06; C12N1/04; C12N9/96; C12P1/00; C12P17/12; (IPC1-7): C07D239/06; C12N9/96; A61K31/505; A61K36/14; C07C257/10; C12N1/04; A61K7/00
Domestic Patent References:
| WO1992004054A1 | 1992-03-19 |
Foreign References:
| US4286660A | 1981-09-01 | |||
| EP0200032A2 | 1986-11-05 | |||
| FR2635113A1 | 1990-02-09 | |||
| US4720458A | 1988-01-19 | |||
| DE3820595A1 | 1989-01-05 |
Other References:
CHEMICAL ABSTRACTS, vol. 104, no. 11, 17 March 1986, Columbus, Ohio, US; abstract no. 85323w, REED R. ET AL.: "Osmotic shock-induced release of low molecular weight metabolites from free-living and immobilized cyanobacteria." page 375;
CHEMICAL ABSTRACTS, vol. 117, no. 17, 26 October 1992, Columbus, Ohio, US; abstract no. 167591q, SEVERIN JOERG ET AL.: "The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria." page 461;
CHEMICAL ABSTRACTS, vol. 115, no. 3, 22 July 1991, Columbus, Ohio, US; abstract no. 29378h, page 784;
CHEMICAL ABSTRACTS, vol. 104, no. 11, 17 March 1986, Columbus, Ohio, US; abstract no. 83993r, SCHUH, W. ET AL.: "The crystal structure of ectoine , a novel amino acid of potential osmoregulatory function." page 259;
CHEMICAL ABSTRACTS, vol. 117, no. 17, 26 October 1992, Columbus, Ohio, US; abstract no. 167591q, SEVERIN JOERG ET AL.: "The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria." page 461;
CHEMICAL ABSTRACTS, vol. 115, no. 3, 22 July 1991, Columbus, Ohio, US; abstract no. 29378h, page 784;
CHEMICAL ABSTRACTS, vol. 104, no. 11, 17 March 1986, Columbus, Ohio, US; abstract no. 83993r, SCHUH, W. ET AL.: "The crystal structure of ectoine , a novel amino acid of potential osmoregulatory function." page 259;
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